1-(2-Cyanophenyl)-4-piperidinecarboxylic+acid
Artikel-Nr:
(PRSI33-494)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-494
Lokale Artikelnummer::
PRSI33-494
Beschreibung:
Recognises a glycoprotein of 44 to 88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI76-731)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-731
Lokale Artikelnummer::
PRSI76-731
Beschreibung:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI76-730)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-730
Lokale Artikelnummer::
PRSI76-730
Beschreibung:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(448421000.)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
448421000
Lokale Artikelnummer::
ACRO448421000
Beschreibung:
Package of 4x25ML bottles
VE:
1 * 100 mL
Artikel-Nr:
(ACRO468021000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
468021000
Lokale Artikelnummer::
ACRO468021000
Beschreibung:
Chemical probes can be used to help establish the
relationship between a molecular target and the broader biological consequences of modulating that target in cells or organisms.
VE:
1 * 100 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
BIS-TRIS-Propan, Sigma-Aldrich®
Artikel-Nr:
(PRSI76-725)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-725
Lokale Artikelnummer::
PRSI76-725
Beschreibung:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI76-727)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-727
Lokale Artikelnummer::
PRSI76-727
Beschreibung:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(USBI038626-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
038626-BIOTIN
Lokale Artikelnummer::
USBI038626-BIOTIN
Beschreibung:
Anti-MSC Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Thiodiglycol, Sigma-Aldrich®
Artikel-Nr:
(PRSI24-316)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-316
Lokale Artikelnummer::
PRSI24-316
Beschreibung:
Anti-BCL5 Recombinant Antibody [Clone: SAIC-23B-22]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(SIAL295795-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
295795-5G
Lokale Artikelnummer::
SIAL295795-5G
Beschreibung:
Ethylbromdifluoracetat, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
METROHM
Beschreibung:
Generatorelektrode für Karl-Fischer-Titrationen, ohne Diaphragma, SGJ 29/22, Für: 831 KF Coulometer
Artikel-Nr:
(BOSSBS-15486R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15486R-A350
Lokale Artikelnummer::
BOSSBS-15486R-A350
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of Zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses Zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localised to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
VE:
1 * 100 µl
Artikel-Nr:
(818-0132)
Lieferant:
Texwipe
Hersteller-Artikelnummer::
TX5811
Lokale Artikelnummer::
TEXWTX5811
Beschreibung:
TexWrite® 22, latex-saturated cellulose cleanroom documentation sheets without organic fillers.
VE:
1 * 2.500 ST
Artikel-Nr:
(PRSI76-734)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-734
Lokale Artikelnummer::
PRSI76-734
Beschreibung:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
VE:
1 * 100 Tests
New Product
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||