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5-Isochinolinborons\u00E4ure+Hydrochlorid
Artikel-Nr:
(BOSSBS-15409R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15409R-A488
Lokale Artikelnummer::
BOSSBS-15409R-A488
Beschreibung:
CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalysing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3960R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3960R-A488
Lokale Artikelnummer::
BOSSBS-3960R-A488
Beschreibung:
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R
Lokale Artikelnummer::
BOSSBS-13314R
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13323R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13323R-HRP
Lokale Artikelnummer::
BOSSBS-13323R-HRP
Beschreibung:
GCSH is a 173 amino acid mitochondrial protein that contains one lipoyl-binding domain and belongs to the gcvH family. Defects in the gene encoding GCSH are the cause of glycine encephalopathy (GCE), an autosomal recessive disease that is also referred to as non-ketotic hyperglycinemia (NKH). Characterized by severe neurological symptoms, patients with GCE have a large amount of glycine accumulated in their body fluids. The gene encoding GCSH maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R-FITC
Lokale Artikelnummer::
BOSSBS-13314R-FITC
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0651R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0651R-HRP
Lokale Artikelnummer::
BOSSBS-0651R-HRP
Beschreibung:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13314R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13314R-A647
Lokale Artikelnummer::
BOSSBS-13314R-A647
Beschreibung:
Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13323R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13323R-A680
Lokale Artikelnummer::
BOSSBS-13323R-A680
Beschreibung:
GCSH is a 173 amino acid mitochondrial protein that contains one lipoyl-binding domain and belongs to the gcvH family. Defects in the gene encoding GCSH are the cause of glycine encephalopathy (GCE), an autosomal recessive disease that is also referred to as non-ketotic hyperglycinemia (NKH). Characterized by severe neurological symptoms, patients with GCE have a large amount of glycine accumulated in their body fluids. The gene encoding GCSH maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12402R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12402R-A350
Lokale Artikelnummer::
BOSSBS-12402R-A350
Beschreibung:
RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5866R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5866R
Lokale Artikelnummer::
BOSSBS-5866R
Beschreibung:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15409R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15409R-A750
Lokale Artikelnummer::
BOSSBS-15409R-A750
Beschreibung:
CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalysing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3960R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3960R-CY5.5
Lokale Artikelnummer::
BOSSBS-3960R-CY5.5
Beschreibung:
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A555
Lokale Artikelnummer::
BOSSBS-6947R-A555
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12528R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12528R-CY3
Lokale Artikelnummer::
BOSSBS-12528R-CY3
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7335R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7335R-HRP
Lokale Artikelnummer::
BOSSBS-7335R-HRP
Beschreibung:
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R-A555
Lokale Artikelnummer::
BOSSBS-12343R-A555
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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