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(R)-Methyl+4,4-difluoropyrrolidine-2-carboxylate+hydrochloride
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(R)-Methyl+4,4-difluoropyrrolidine-2-carboxylate+hydrochloride
Artikel-Nr:
(BOSSBS-13258R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13258R-FITC
Lokale Artikelnummer::
BOSSBS-13258R-FITC
Beschreibung:
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-A680
Lokale Artikelnummer::
BOSSBS-1350R-A680
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4989R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4989R-A750
Lokale Artikelnummer::
BOSSBS-4989R-A750
Beschreibung:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasised by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1160R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1160R-FITC
Lokale Artikelnummer::
BOSSBS-1160R-FITC
Beschreibung:
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5357R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5357R-CY7
Lokale Artikelnummer::
BOSSBS-5357R-CY7
Beschreibung:
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4989R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4989R-A350
Lokale Artikelnummer::
BOSSBS-4989R-A350
Beschreibung:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A680
Lokale Artikelnummer::
BOSSBS-6947R-A680
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerises with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5663R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5663R-HRP
Lokale Artikelnummer::
BOSSBS-5663R-HRP
Beschreibung:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11462R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11462R-A647
Lokale Artikelnummer::
BOSSBS-11462R-A647
Beschreibung:
NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7896R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7896R-FITC
Lokale Artikelnummer::
BOSSBS-7896R-FITC
Beschreibung:
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13016R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13016R-FITC
Lokale Artikelnummer::
BOSSBS-13016R-FITC
Beschreibung:
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3302R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3302R-FITC
Lokale Artikelnummer::
BOSSBS-3302R-FITC
Beschreibung:
Neuronal Marker The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9521R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9521R-CY5
Lokale Artikelnummer::
BOSSBS-9521R-CY5
Beschreibung:
Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5389R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5389R-A555
Lokale Artikelnummer::
BOSSBS-5389R-A555
Beschreibung:
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6405R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6405R-FITC
Lokale Artikelnummer::
BOSSBS-6405R-FITC
Beschreibung:
Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2721R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2721R-A488
Lokale Artikelnummer::
BOSSBS-2721R-A488
Beschreibung:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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