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cis-2-Benzylamino-cyclohexanol+hydrochloride
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cis-2-Benzylamino-cyclohexanol+hydrochloride
Artikel-Nr:
(PRSI77-051)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-051
Lokale Artikelnummer::
PRSI77-051
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI77-052)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-052
Lokale Artikelnummer::
PRSI77-052
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI77-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-048
Lokale Artikelnummer::
PRSI77-048
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI77-045)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-045
Lokale Artikelnummer::
PRSI77-045
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,1 mg
New Product
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-TCR gamma/delta Mouse Monoclonal Antibody [clone: B1] (Ultra-LEAF™)
Artikel-Nr:
(BLEG331229)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
331229
Lokale Artikelnummer::
BLEG331229
Beschreibung:
Anti-TCR gamma/delta Mouse Monoclonal Antibody [clone: B1] (TotalSeq™-A0139)
VE:
1 * 10 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(USBIG9039-35)
Lieferant:
US Biological
Hersteller-Artikelnummer::
G9039-35
Lokale Artikelnummer::
USBIG9039-35
Beschreibung:
Anti-Guanine Nucleotide Binding Protein, beta 5 subunit Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBIN2050-06P)
Lieferant:
US Biological
Hersteller-Artikelnummer::
N2050-06P
Lokale Artikelnummer::
USBIN2050-06P
Beschreibung:
Anti-Nerve Growth Factor, beta Rabbit Monoclonal Antibody [clone: 9i179]
VE:
1 * 100 µl
Artikel-Nr:
(USBIP4186-28N-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P4186-28N-APC
Lokale Artikelnummer::
USBIP4186-28N-APC
Beschreibung:
Anti-PI 4 Kinase Type 2 beta Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(PRSI90-507)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-507
Lokale Artikelnummer::
PRSI90-507
Beschreibung:
Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesised as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1910R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1910R-CY5
Lokale Artikelnummer::
BOSSBS-1910R-CY5
Beschreibung:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1910R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1910R-CY5.5
Lokale Artikelnummer::
BOSSBS-1910R-CY5.5
Beschreibung:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:
1 * 100 µl
Artikel-Nr:
(USBIL8015-03G)
Lieferant:
US Biological
Hersteller-Artikelnummer::
L8015-03G
Lokale Artikelnummer::
USBIL8015-03G
Beschreibung:
Anti-Lymphotoxin beta Receptor Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 7H156]
VE:
1 * 120 Tests
Artikel-Nr:
(USBIP9052-06B-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9052-06B-AP
Lokale Artikelnummer::
USBIP9052-06B-AP
Beschreibung:
Anti-Propionyl Coenzyme A Carboxylase beta Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIH1832-98D1)
Lieferant:
US Biological
Hersteller-Artikelnummer::
H1832-98D1
Lokale Artikelnummer::
USBIH1832-98D1
Beschreibung:
Anti-Heat Shock Protein 90, beta Mouse Monoclonal Antibody [clone: 10F733]
VE:
1 * 100 µG
Artikel-Nr:
(USBIH1834-55N-200)
Lieferant:
US Biological
Hersteller-Artikelnummer::
H1834-55N-200
Lokale Artikelnummer::
USBIH1834-55N-200
Beschreibung:
Anti-Heat Shock Protein 90, beta Mouse Monoclonal Antibody [clone: 7L20]
VE:
1 * 200 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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