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3,5,7-Trifluoroadamantane-1-carboxylic+acid
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3,5,7-Trifluoroadamantane-1-carboxylic+acid
Artikel-Nr:
(BOSSBS-3228R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3228R-CY5
Lokale Artikelnummer::
BOSSBS-3228R-CY5
Beschreibung:
Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3228R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3228R-CY3
Lokale Artikelnummer::
BOSSBS-3228R-CY3
Beschreibung:
Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13245R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13245R-HRP
Lokale Artikelnummer::
BOSSBS-13245R-HRP
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. G gamma4 interacts with beta-1 and beta-2, but not with beta-3. It is expressed in brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11153R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11153R
Lokale Artikelnummer::
BOSSBS-11153R
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1419R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1419R-A350
Lokale Artikelnummer::
BOSSBS-1419R-A350
Beschreibung:
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6058R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6058R
Lokale Artikelnummer::
BOSSBS-6058R
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9585R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9585R-CY5
Lokale Artikelnummer::
BOSSBS-9585R-CY5
Beschreibung:
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11679R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11679R-A350
Lokale Artikelnummer::
BOSSBS-11679R-A350
Beschreibung:
The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0771R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0771R-A647
Lokale Artikelnummer::
BOSSBS-0771R-A647
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0771R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0771R-FITC
Lokale Artikelnummer::
BOSSBS-0771R-FITC
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB281915-200)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB281915-200
Lokale Artikelnummer::
ABCAAB281915-200
Beschreibung:
Anti-GABA A Receptor beta 2/GABRB2+GABA A Receptor gamma 2/GABRG2+GABA A Receptor alpha 1 Rabbit Monoclonal Antibody [clone: 1F4]
VE:
1 * 200 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-13245R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13245R-A750
Lokale Artikelnummer::
BOSSBS-13245R-A750
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. G gamma4 interacts with beta-1 and beta-2, but not with beta-3. It is expressed in brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7558R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7558R-CY7
Lokale Artikelnummer::
BOSSBS-7558R-CY7
Beschreibung:
Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4559R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4559R-FITC
Lokale Artikelnummer::
BOSSBS-4559R-FITC
Beschreibung:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3238R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3238R-CY3
Lokale Artikelnummer::
BOSSBS-3238R-CY3
Beschreibung:
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3238R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3238R-CY7
Lokale Artikelnummer::
BOSSBS-3238R-CY7
Beschreibung:
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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