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Benzyl+(cis-4-(hydroxymethyl)cyclohexyl)carbamate
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Benzyl+(cis-4-(hydroxymethyl)cyclohexyl)carbamate
Lieferant:
Uptima
Beschreibung:
N-Octyl-β-D-glucopyranosid
Lieferant:
FLUOROCHEM
Beschreibung:
4-Brombenzylchlorid
Lieferant:
MP Biomedicals
Beschreibung:
Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Artikel-Nr:
(438542E)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC438542E
Beschreibung:
(5-Brom-4-chlor-3-indolyl-ß-D-glucuronid)cyclohexyl-Ammoniumsalz (X-GlcA) ist ein chromogenes Substrat zur Bestimmung der ß-Glucuronidase (GUS) Gene.
VE:
1 * 100 mg
Artikel-Nr:
(ICNA04856126)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
04856126
Lokale Artikelnummer::
ICNA04856126
Beschreibung:
DL-Dithiothreitol is also known as Clelands reagent; Protective agent for sulfhydryl groups (-SH). Quantitatively reduces disulfides (-S-S- to -SH). In this reaction the DTT is oxidized to the cyclic disulfide which ensures the reduction of other disulfides in solution. Disulfide reduction occurs quickly at pH 8.
Dithiothreitol is useful for stabilizing sulfhydryl containing enzymes. Effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Useful for stabilizing sulfhydryl-containing enzymes.
VE:
1 * 5 g
Lieferant:
Uptima
Beschreibung:
X-Gal (5-Brom-4-chlor-3-indolyl-ß-D-galactopyranosid)
Artikel-Nr:
(REST31900)
Lieferant:
Restek
Hersteller-Artikelnummer::
31900
Lokale Artikelnummer::
REST31900
Beschreibung:
Consists of 65 components, those are acenaphthene, acenaphthylene, acetophenone, anthracene, benzanthracene, benzopyrene, benzofluoranthene, benzoperylene, benzofluoranthene, benzyl butyl phthalate, biphenyl, bismethane, bisether, bisphthalate, 4-bromophenyl-phenylether, carbazole, 4-chloroaniline, 4-chloro-3-methylphenol, 2-chloronaphthalene, 2-chlorophenol, 4-chlorophenyl-phenylether, chrysene, dibenzanthracene, dibenzofuran, 3,3'-dichlorobenzidine, 2,4-dichlorophenol, diethylphthalate, 2,4-dimethylphenol, dimethylphthalate, di-n-butylphthalate, 4,6-dinitro-2-methylphenol , 2,4-dinitrophenol, 2,4-dinitrotoluene, 2,6-dinitrotoluene, di-n-octyl phthalate, diphenylamine *,fluoranthene, fluorene, hexachlorobenzene, hexachloro-1,3-butadiene , hexachlorocyclopentadiene, hexachloroethane, indenopyrene, isophorone, 2-methylnaphthalene, 2-methylphenol , 3-methylphenol, 4-methylphenol , naphthalene, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, nitrobenzene, 2-nitrophenol, 4-nitrophenol, n-nitroso-di-n-propylamine, 2,2'-oxybis, pentachlorophenol, phenanthrene, phenol, pyrene, 1,2,4,5-tetrachlorobenzene, 2,3,4,6-tetrachlorophenol, 2,4,5-trichlorophenol and 2,4,6-trichlorophenol.
VE:
1 * 1 Ampull
Artikel-Nr:
(PRSI79-710)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-710
Lokale Artikelnummer::
PRSI79-710
Beschreibung:
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
VE:
1 * 100 µG
Artikel-Nr:
(32751-100G)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
32751-100G
Lokale Artikelnummer::
HONC32751-100G
Beschreibung:
Eriochromschwarz T Reag. Ph. Eur. Indikator für die Metalltitration, Fluka™
VE:
1 * 100 g
Lieferant:
Uptima
Beschreibung:
Dithiothreitol (DTT, Cleland's Reagenz)
Artikel-Nr:
(PRSI33-371)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-371
Lokale Artikelnummer::
PRSI33-371
Beschreibung:
This mAb recognises a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This mAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This mAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesised by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(SIAL191531-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
191531-5G
Lokale Artikelnummer::
SIAL191531-5G
Beschreibung:
4-tert-Butyl-α-chlortoluol, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
MP Biomedicals
Beschreibung:
Storage: Store at Room Temperature (15-30 °C).
D-myo-Inositol is a component of membrane phospholipids, glycosylphophatidylinositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. It is a growth factor for animals as well as microorganisms. Myo-Inositol is the most abundant form of polyols that serves as a structural element of secondary messengers in eukaryotic cells. Inositol or cyclohexane-1,2,3,4,5,6-hexol is a chemical compound, a sixfold alcohol (polyol) of cyclohexane. It exists in nine possible stereoisomers, of which the most prominent form, widely occurring in nature, is cis-1,2,3,5-trans-4,6-cyclohexanehexol, or myo-inositol (former name meso-inositol). Inositol is a carbohydrate, though not a classical sugar. It has a taste which has been assayed at half the sweetness of table sugar. Used as a lipotropic agent. A component of membrane phospholipids, glycosylphosphatidylinositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. In addition, inositol serves as an important component of the structural lipids phosphatidylinositol (PI) and its various phosphates, the phosphatidylinositol phosphate (PIP) lipids.
Artikel-Nr:
(MOLEM78925342)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M78925342
Lokale Artikelnummer::
MOLEM78925342
Beschreibung:
Xylenolorange Tetranatriumsalz
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
MP Biomedicals
Beschreibung:
Bromthymolblau Natriumsalz, Pulver
Lieferant:
Spectrum Chemical
Beschreibung:
Polysorbate 80, FCC is used as a wetting agent. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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