Bis(1,5-cyclooctadien)iridium(I)tetrafluoroborat
Lieferant:
BIOLEGEND INC
Beschreibung:
Human recombinant GMP IL-15
Lieferant:
Sigma-Aldrich
Beschreibung:
Nickel(II)acetylacetonat, Sigma-Aldrich®
Lieferant:
UVP ULTRA VIOLET PRODUCTS
Beschreibung:
Filter für UV-Lampen, Für: XX-15S
Artikel-Nr:
(SIAL567205-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
567205-100G
Lokale Artikelnummer::
SIAL567205-100G
Beschreibung:
Tetramethylthiurammonosulfid
VE:
1 * 100 g
Artikel-Nr:
(ORIGTA309488)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA309488
Lokale Artikelnummer::
ORIGTA309488
Beschreibung:
Anti-TRPC5 Mouse Monoclonal Antibody [clone: S67-15]
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-505)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-505
Lokale Artikelnummer::
PRSI90-505
Beschreibung:
Interleukin-15 (IL-15) has a broad spectrum of biological activities. It is crucial for the development, proliferation, survival and differentiation of multiple cells from both innate and adaptive immune systems. IL-15 up-regulation has a central role in the development of several autoimmune or chronic inflammatory disorders. Targeting IL-15 or its receptor may have a valuable impact on the treatment of immune-mediated diseases. IL-15 participates in the development of important immune antitumour mechanisms. It activates CD8(+) T cells, natural killer (NK) cells, NK T cells, and can promote the formation of antitumour antibodies. IL-15 can also protect T effector cells from the action of T regulatory cells and reverse tolerance to tumour-associated antigens. In pre-clinical studies IL-15 has been found to demonstrate potentiated antitumour effects following pre-association with IL-15Ralpha, or when used in combination with chemotherapy, adoptive therapy, monoclonal antibodies, and tumour vaccines.
Application: Useful for immunofluorescent staining and flow cytometric analysis to identify and enumerate IL-15Ralpha expressing cells within mixed cell populations.
VE:
1 * 1 Vial
Lieferant:
Agilent
Beschreibung:
Ferrule, 85% vespel/15% graphite, 1/8", 15% Graphit/85% Vespel®
Artikel-Nr:
(BOSSBS-12248R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-CY3
Lokale Artikelnummer::
BOSSBS-12248R-CY3
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Kupfer(II)acetylacetonat, Sigma-Aldrich®
Artikel-Nr:
(USBI040939)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040939
Lokale Artikelnummer::
USBI040939
Beschreibung:
Anti-RECK Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI044078-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
044078-BIOTIN
Lokale Artikelnummer::
USBI044078-BIOTIN
Beschreibung:
Anti-ZFYVE16 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Lieferant:
IKA
Beschreibung:
Hose, 2×1,5 m, PVC, Ø 8 mm, Für: -
Lieferant:
Sigma-Aldrich
Beschreibung:
Kupfer(II)acetylacetonat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
PIPES, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-3769R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R-A750
Lokale Artikelnummer::
BOSSBS-3769R-A750
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12327R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12327R-A647
Lokale Artikelnummer::
BOSSBS-12327R-A647
Beschreibung:
The gene encoding the mouse alloantigen, Ly-6C, maps to chromosome 15 and encodes a 131 amino acid protein that belongs to the Ly-6 family of glycosyl-phosphatidylinositol (GPI)-linked proteins. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. Murine Ly-6 molecules have unique patterns of tissue expression during hematopoiesis from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6C is predominantly expressed on murine peripheral CD8 T cells. Ly-6C is involved in endothelial adhesion, the killing of target cells by CTLs, inducing TCR-mediated activation of IL-2 and IFN-?production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation.
VE:
1 * 100 µl
Preis auf Anfrage
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