Bis(3-nitrophenyl)disulfid
Artikel-Nr:
(SIAL803316-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
803316-50MG
Lokale Artikelnummer::
SIAL803316-50MG
Beschreibung:
The SPDP reagents are a unique group of amine- and sulfhydryl-reactive heterobifunctional crosslinkers. Whether they are used to form amine-to-amine or amine-to-sulfhydryl crosslinks among molecules, the SPDP reagents produce disulfide-containing linkages that can be cleaved later with reducing agents such as dithiothreitol (DTT).
VE:
1 * 50 mg
Artikel-Nr:
(PRSI91-108)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-108
Lokale Artikelnummer::
PRSI91-108
Beschreibung:
beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.
VE:
1 * 50 µG
Artikel-Nr:
(COBBBB-5834-250M)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
BB-5834-250M
Lokale Artikelnummer::
COBBBB-5834-250M
Beschreibung:
4-Brom-2-nitrophenylboronsäure
VE:
1 * 250 mg
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Artikel-Nr:
(PRSI91-179)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-179
Lokale Artikelnummer::
PRSI91-179
Beschreibung:
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-732)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-732
Lokale Artikelnummer::
PRSI91-732
Beschreibung:
Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).
VE:
1 * 50 µG
Lieferant:
Alfa Aesar
Beschreibung:
Nitrendipine
Artikel-Nr:
(SIAL553654-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
553654-10G
Lokale Artikelnummer::
SIAL553654-10G
Beschreibung:
4'-Methoxy-3'-nitroacetophenon, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(PRSI91-206)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-206
Lokale Artikelnummer::
PRSI91-206
Beschreibung:
Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF- beta superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
VE:
1 * 50 µG
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Methoxy-2-nitrophenylboronsäure
Artikel-Nr:
(CHMPFL13848.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13848.POR
Lokale Artikelnummer::
CHMPFL13848.POR
Beschreibung:
3'-Fluor-4'-nitroacetanilid
VE:
1 * 1 ST
Lieferant:
COMBI-BLOCKS
Beschreibung:
5-(4-Boc-piperazino)-2-nitroanisol
Artikel-Nr:
(PRSI96-768)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-768
Lokale Artikelnummer::
PRSI96-768
Beschreibung:
Vascular endothelial growth factor (VEGF) is also known as vascular permeability factor (VPF) and VEGF-A, and is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized.
VE:
1 * 20 µG
Artikel-Nr:
(PRSI92-373)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-373
Lokale Artikelnummer::
PRSI92-373
Beschreibung:
Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-581)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-581
Lokale Artikelnummer::
PRSI33-581
Beschreibung:
It recognises a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesised on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesised N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
VE:
1 * 100 µG
New Product
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Cyan-2-nitrophenylboronsäure
Artikel-Nr:
(FLUO018587-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018587-1G
Lokale Artikelnummer::
FLUO018587-1G
Beschreibung:
4,5-Dimethoxy-2-nitrobenzylalkohol
VE:
1 * 1 g
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