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CROSSTEX
Artikel-Nr:
(BOSSBS-1911R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1911R-A488
Lokale Artikelnummer::
BOSSBS-1911R-A488
Beschreibung:
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1388-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1388-50
Lokale Artikelnummer::
BSENR-1388-50
Beschreibung:
Neurofilaments contain three intermediate filament proteins: light (68 kDa), medium (160 kDa) and heavy (200 kDa). Neurofilament heavy (NF200 or NF-H) is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Lieferant:
Biotium
Beschreibung:
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Artikel-Nr:
(BOSSBS-13356R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13356R-A750
Lokale Artikelnummer::
BOSSBS-13356R-A750
Beschreibung:
May participate in forming intercisternal cross-bridges of the Golgi complex.
VE:
1 * 100 µl
Artikel-Nr:
(BC07)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
BC07
Lokale Artikelnummer::
GENOBC07
Beschreibung:
Dithiobis(succinimidyl propionate) Homobifunctional Cross Linker.
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-1587R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1587R-A750
Lokale Artikelnummer::
BOSSBS-1587R-A750
Beschreibung:
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyses the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Artikel-Nr:
(BOSSBS-8589R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8589R
Lokale Artikelnummer::
BOSSBS-8589R
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Lieferant:
Avantor Fluid Handling
Beschreibung:
Mechanische Innovationen reduzieren das Risiko von Flüssigkeitsübertritt und Kontamination. Eine Gegenverbindung wird mit einem High Flow-Stecker hergestellt.
Lieferant:
Avantor Fluid Handling
Beschreibung:
Mechanische Innovationen reduzieren das Risiko von Flüssigkeitsübertritt und Kontamination. Eine Gegenverbindung wird mit einer Medium Flow Buchse hergestellt.
Artikel-Nr:
(BOSSBS-8589R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8589R-A488
Lokale Artikelnummer::
BOSSBS-8589R-A488
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8589R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8589R-A350
Lokale Artikelnummer::
BOSSBS-8589R-A350
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4206R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4206R-A555
Lokale Artikelnummer::
BOSSBS-4206R-A555
Beschreibung:
Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This is a highly cross-adsorbed goat anti-mouse IgG (H L) secondary antibody labeled with our bright and photostable CF® Dyes. To minimise cross-reactivity, the antibody has been adsorbed against bovine, horse, human, rabbit, and swine serum. This antibody is not cross-adsorbed against rat. For staining rat tissue, or co-staining with rat antibodies, we recommend using Goat Anti-Mouse IgG (H L), Highly Cross-Adsorbed (Min x Rat).
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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