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Dimethyl+cubane-1,4-dicarboxylate
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Dimethyl+cubane-1,4-dicarboxylate
Artikel-Nr:
(SIALW230901-4KG-K)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
W230901-4KG-K
Lokale Artikelnummer::
SIALW230901-4KG-K
Beschreibung:
(±)-β-Citronellol, Sigma-Aldrich®
VE:
1 * 4 kg
Lieferant:
Sigma-Aldrich
Beschreibung:
Spermin (N,N'-Bis(3-aminopropyl)-1,4-butandiamin), Sigma-Aldrich®
Artikel-Nr:
(MOLEM49664205)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M49664205
Lokale Artikelnummer::
MOLEM49664205
Beschreibung:
1,4-Dichlor-2-buten (Gemisch der cis- und trans-Isomeren)
VE:
1 * 500 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(HONC40301H-2.5L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
40301H-2.5L
Lokale Artikelnummer::
HONC40301H-2.5L
Beschreibung:
2-Propanol ≥99,8% VLSI, Halbleiter-Qualität (Honeywell 17604)
VE:
1 * 2,5 L
Artikel-Nr:
(BOSSBS-11217R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11217R-CY5
Lokale Artikelnummer::
BOSSBS-11217R-CY5
Beschreibung:
Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1). Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1). MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2). MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34 (3). MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3). In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy (4).
VE:
1 * 100 µl
Artikel-Nr:
(681675-1)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
681675-1
Lokale Artikelnummer::
CALB681675-1
Beschreibung:
Wortmannin is a cell-permeable, fungal metabolite that acts as a potent, selective and irreversible inhibitor of phosphatidylinositol 3-kinase in purified preparations and cytosolic fractions (IC50 = 5 nm).
VE:
1 * 1 mg
Artikel-Nr:
(SIAL252336-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
252336-5G
Lokale Artikelnummer::
SIAL252336-5G
Beschreibung:
2,6-Dimethylphenylisocyanat, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
Cayman Chemical
Beschreibung:
Metamizole (sodium salt) is a nonopioid prodrug that is rapidly hydrolyzed to the metabolites 4-methylaminoantipyrine (MAA) and 4-aminoantipyrine (AA), which have analgesic and antipyretic effects. MAA has been shown to inhibit COX activity 8-9-fold more potently than AA (COX-1: IC<sub>50</sub><sup>S</sup>= 2,6 and 20,8 µM, respectively, and COX-2: IC<sub>50</sub><sup>S</sup>= 4,7 and 41,8 µM, respectively). These metabolites can be further acylated with arachidonic acid to form compounds that can bind to central and peripheral cannabinoid (CB<sub>1</sub> and CB<sub>2</sub>) receptors and TRPV1 receptors at low micromolar concentrations.
Lieferant:
Thermo Scientific
Beschreibung:
2-Propanol 99+%, erfüllt analytische Spezifikationen von Ph.Eur.
Artikel-Nr:
(BOSSBS-11217R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11217R-A555
Lokale Artikelnummer::
BOSSBS-11217R-A555
Beschreibung:
Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1). Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1). MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2). MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34 (3). MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3). In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy (4).
VE:
1 * 100 µl
Lieferant:
Molekula
Beschreibung:
POPSO (β,β'-Dihydroxypiperazin-1,4-dipropansulfonsäure) Dihydrat
Artikel-Nr:
(BOSSBS-4901R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4901R-A750
Lokale Artikelnummer::
BOSSBS-4901R-A750
Beschreibung:
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Artikel-Nr:
(BNUM0198-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0198-50
Lokale Artikelnummer::
BTIUBNUM0198-50
Beschreibung:
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Lieferant:
Biotium
Beschreibung:
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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