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(1-Phenyl-1H-pyrazol-4-yl)methanol
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(1-Phenyl-1H-pyrazol-4-yl)methanol
Artikel-Nr:
(BOSSBS-3027R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3027R
Lokale Artikelnummer::
BOSSBS-3027R
Beschreibung:
Anti-PRKAB1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7531R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7531R-A350
Lokale Artikelnummer::
BOSSBS-7531R-A350
Beschreibung:
The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn’t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5125R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5125R-HRP
Lokale Artikelnummer::
BOSSBS-5125R-HRP
Beschreibung:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13239R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13239R-A488
Lokale Artikelnummer::
BOSSBS-13239R-A488
Beschreibung:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7947R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7947R-A750
Lokale Artikelnummer::
BOSSBS-7947R-A750
Beschreibung:
Abhydrolase domain containing 3 (ABHD3) belongs to the AB hydrolase superfamily. It has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7947R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7947R-A647
Lokale Artikelnummer::
BOSSBS-7947R-A647
Beschreibung:
Abhydrolase domain containing 3 (ABHD3) belongs to the AB hydrolase superfamily. It has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12910R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12910R-A680
Lokale Artikelnummer::
BOSSBS-12910R-A680
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated Signalling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3152R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3152R-A750
Lokale Artikelnummer::
BOSSBS-3152R-A750
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13170R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13170R-HRP
Lokale Artikelnummer::
BOSSBS-13170R-HRP
Beschreibung:
The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12910R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12910R-A350
Lokale Artikelnummer::
BOSSBS-12910R-A350
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6660R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6660R-A350
Lokale Artikelnummer::
BOSSBS-6660R-A350
Beschreibung:
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity; Skeletal muscle, heart, colon, testis, ovary and pancreas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13379R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13379R-A750
Lokale Artikelnummer::
BOSSBS-13379R-A750
Beschreibung:
GLT25D2 is a 626 amino acid protein that localizes to endoplasmic reticulum lumen and belongs to the glycosyltransferase 25 family. Possessing beta-galactosyltransferase activity, GLT25D2 transports beta-galactose to hydroxylysine residues on collagen but lacks glucosyltransferase activity. GLT25D2 is expressed in skeletal muscle and brain, and is encoded by a gene located on human chromosome 1q25.3, a region associated with the hereditary prostate cancer (HPC1) locus. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12910R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12910R-A750
Lokale Artikelnummer::
BOSSBS-12910R-A750
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated Signalling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3154R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3154R-A555
Lokale Artikelnummer::
BOSSBS-3154R-A555
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3154R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3154R-HRP
Lokale Artikelnummer::
BOSSBS-3154R-HRP
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6660R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6660R-CY5
Lokale Artikelnummer::
BOSSBS-6660R-CY5
Beschreibung:
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity; Skeletal muscle, heart, colon, testis, ovary and pancreas.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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