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Essigs\\u00E4ure-[D1]
Artikel-Nr:
(BOSSBS-11234R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11234R-A750
Lokale Artikelnummer::
BOSSBS-11234R-A750
Beschreibung:
The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1; however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.
VE:
1 * 100 µl
Artikel-Nr:
(ABNOMAB15450)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB15450
Lokale Artikelnummer::
ABNOMAB15450
Beschreibung:
Mouse monoclonal antibody raised against native mouse H2-D1.
VE:
1 * 100 µG
Artikel-Nr:
(USBI123173)
Lieferant:
US Biological
Hersteller-Artikelnummer::
123173
Lokale Artikelnummer::
USBI123173
Beschreibung:
Anti-AKR1D1 Mouse Monoclonal Antibody [clone: 1C2]
VE:
1 * 100 µG
Artikel-Nr:
(BSBTPA1245-2)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PA1245-2
Lokale Artikelnummer::
BSBTPA1245-2
Beschreibung:
Polyclonal antibody for Cyclin D1/CCND1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. Cyclin D1/CCND1 information: Molecular Weight: 33729 MW; Subcellular Localization: Nucleus . Cytoplasm . Membrane . Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated to the nucleus through interaction with KIP/CIP family members.
VE:
1 * 100 µG
Artikel-Nr:
(BSBTPA1231)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PA1231
Lokale Artikelnummer::
BSBTPA1231
Beschreibung:
Anti-Dopamine Receptor D1 Rabbit Polyclonal Antibody
VE:
1 * 0,1 mg
Artikel-Nr:
(USBI126188)
Lieferant:
US Biological
Hersteller-Artikelnummer::
126188
Lokale Artikelnummer::
USBI126188
Beschreibung:
Anti-EFHD1 Mouse Monoclonal Antibody [clone: 1H7]
VE:
1 * 100 µG
Artikel-Nr:
(USBI043082-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043082-BIOTIN
Lokale Artikelnummer::
USBI043082-BIOTIN
Beschreibung:
Anti-TNFRSF8 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(ORIGCF505225)
Lieferant:
OriGene
Hersteller-Artikelnummer::
CF505225
Lokale Artikelnummer::
ORIGCF505225
Beschreibung:
Anti-PIK3CG Mouse Monoclonal Antibody [clone: D1]
VE:
1 * 100 µG
Artikel-Nr:
(PRSI24-257)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-257
Lokale Artikelnummer::
PRSI24-257
Beschreibung:
Anti-Flavivirus Group Antigen Recombinant Antibody [Clone: D1-4G2-4-15 (4G2)]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(ABNOMAB15451)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB15451
Lokale Artikelnummer::
ABNOMAB15451
Beschreibung:
Mouse monoclonal antibody raised against native mouse H2-D1.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-11860R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-CY5
Lokale Artikelnummer::
BOSSBS-11860R-CY5
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-CY7
Lokale Artikelnummer::
BOSSBS-11860R-CY7
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11234R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11234R-A555
Lokale Artikelnummer::
BOSSBS-11234R-A555
Beschreibung:
The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1; however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-FITC
Lokale Artikelnummer::
BOSSBS-11860R-FITC
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6992R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6992R
Lokale Artikelnummer::
BOSSBS-6992R
Beschreibung:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-A750
Lokale Artikelnummer::
BOSSBS-11860R-A750
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation Signalling.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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