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Ethyl-2-naphthoyl+formate
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Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-2803R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2803R-A750
Lokale Artikelnummer::
BOSSBS-2803R-A750
Beschreibung:
Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-140)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-140
Lokale Artikelnummer::
PRSI91-140
Beschreibung:
Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed; it is abundant in testis, skeletal muscle, and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-794)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-794
Lokale Artikelnummer::
PRSI26-794
Beschreibung:
EIF5 catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
VE:
1 * 50 µG
Artikel-Nr:
(FLUO009181-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
009181-5G
Lokale Artikelnummer::
FLUO009181-5G
Beschreibung:
1-Ethyl-3-methylimidazoliumtrifluormethansulfonat
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(PRSI28-578)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-578
Lokale Artikelnummer::
PRSI28-578
Beschreibung:
Foxd1 is transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Mice lacking Foxd1 show disrupted cell identity in the ventrotemporal area of the retina and aberrant morphogenesis of the optic chiasm. Their kidneys remain fused, have a disorganised ureteric tree and fail to ascend to a lumbar position.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-593)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-593
Lokale Artikelnummer::
PRSI28-593
Beschreibung:
RelB is a member of the Rel/nuclear factor (NF)-kappa B family of transcription factors, defects in RelB affects antigen presenting cells and the formation of lymphoid organs. Targeted disruption of the Rel/NF-kappaB family members NF-kappaB2, encoding p100/p52, and RelB in mice results in anatomical defects of secondary lymphoid tissues.
VE:
1 * 100 µG
Artikel-Nr:
(FLUO022409-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
022409-1G
Lokale Artikelnummer::
FLUO022409-1G
Beschreibung:
4-Ethyl-4'-methylbenzhydrol
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(PRSI28-914)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-914
Lokale Artikelnummer::
PRSI28-914
Beschreibung:
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-425)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-425
Lokale Artikelnummer::
PRSI79-425
Beschreibung:
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-986)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-986
Lokale Artikelnummer::
PRSI26-986
Beschreibung:
RP11-529I10.4 (DPCD) belongs to the DPCD family. It may play a role in the formation or function of ciliated cells. Deletion of the DPCD gene may be a cause of primary ciliary dyskinesia (PCD).
VE:
1 * 50 µG
Artikel-Nr:
(EHERC11502800)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C11502800
Lokale Artikelnummer::
EHERC11502800
Beschreibung:
(±)-Ethyl-2-chlorpropionat
VE:
1 * 0,1 g
Artikel-Nr:
(PRSI79-206)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-206
Lokale Artikelnummer::
PRSI79-206
Beschreibung:
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-653)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-653
Lokale Artikelnummer::
PRSI91-653
Beschreibung:
Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
VE:
1 * 50 µG
Lieferant:
Thermo Scientific
Beschreibung:
Ethyl-6-chlornicotinat
Artikel-Nr:
(PRSI91-175)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-175
Lokale Artikelnummer::
PRSI91-175
Beschreibung:
Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Glycerol phosphate disodium salt was used in a novel microplate-based chromatin immunoprecipitation method to immunoprecipitate DNA from rat mesangial cells in a 96-well format.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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