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3\'-Benzyloxyacetophenon
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3\'-Benzyloxyacetophenon
Artikel-Nr:
(PRSI29-569)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-569
Lokale Artikelnummer::
PRSI29-569
Beschreibung:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
VE:
1 * 50 µG
Lieferant:
COMBI-BLOCKS
Beschreibung:
1-Ethyl-1H-pyrazol-4-boronsäure
Artikel-Nr:
(PRSI6905)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6905
Lokale Artikelnummer::
PRSI6905
Beschreibung:
ZBTB40 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB40, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Single nucleotide polymorphisms near ZBTB40 have been linked to differences in bone mineral density of the hip and lumbar spine, and had a significant association with low-trauma fractures suggesting that ZBTB40 may be involved in bone development and formation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-154)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-154
Lokale Artikelnummer::
PRSI36-154
Beschreibung:
The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-153)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-153
Lokale Artikelnummer::
PRSI36-153
Beschreibung:
The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
VE:
1 * 100 µG
Artikel-Nr:
(COBBHC-6334-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-6334-1G
Lokale Artikelnummer::
COBBHC-6334-1G
Beschreibung:
Ethyl 4-oxo-7-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(COBBHC-2396-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-2396-1G
Lokale Artikelnummer::
COBBHC-2396-1G
Beschreibung:
Ethyl-5-amino-4-cyan-1-(4-fluorphenyl)-1H-pyrazol-3-carboxylat
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(PRSI91-161)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-161
Lokale Artikelnummer::
PRSI91-161
Beschreibung:
Tumor Necrosis Factor beta (TNF- beta ) is a secreted protein belonging to the tumor necrosis factor family. TNF- beta binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF- beta forms heterotrimers with lymphotoxin-beta, which anchors TNF- beta to the cell surface. TNF- beta mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF- beta is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-621)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-621
Lokale Artikelnummer::
PRSI91-621
Beschreibung:
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells.
VE:
1 * 50 µG
Artikel-Nr:
(ENAMEN30010285.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN30010285.1G
Lokale Artikelnummer::
ENAMEN30010285.1G
Beschreibung:
Ethyl-5-amino-1-(3-chlorphenyl)-1H-pyrazol-4-carboxylat
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(COBBHC-2296-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-2296-1G
Lokale Artikelnummer::
COBBHC-2296-1G
Beschreibung:
Ethyl-5-amino-1-(2-bromphenyl)-4-cyan-1H-pyrazol-3-carboxylat
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(COBBHC-2313-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-2313-1G
Lokale Artikelnummer::
COBBHC-2313-1G
Beschreibung:
Ethyl-5-amino-1-(3-chlorphenyl)-4-cyan-1H-pyrazol-3-carboxylat
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-7571R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7571R-A488
Lokale Artikelnummer::
BOSSBS-7571R-A488
Beschreibung:
Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).
VE:
1 * 100 µl
Artikel-Nr:
(PRSIXP-5227)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5227
Lokale Artikelnummer::
PRSIXP-5227
Beschreibung:
Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF).
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXW-8087)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-8087
Lokale Artikelnummer::
PRSIXW-8087
Beschreibung:
SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity). It’s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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