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1-Cyclopropyl-4-piperidinone
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1-Cyclopropyl-4-piperidinone
Artikel-Nr:
(BOSSBS-8998R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R
Lokale Artikelnummer::
BOSSBS-8998R
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-A555
Lokale Artikelnummer::
BOSSBS-6425R-A555
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-145-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-145-100
Lokale Artikelnummer::
BSENR-145-100
Beschreibung:
ATG10 plays a role in autophagy. It is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugations and modificatioon of a soluble form of MAPLC3 1A, a homolog of yeast ATG8, to a membrane bound form. It is also able to directly interact either with ATG5 or ATG7.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1428R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1428R-CY7
Lokale Artikelnummer::
BOSSBS-1428R-CY7
Beschreibung:
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1980R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1980R-A350
Lokale Artikelnummer::
BOSSBS-1980R-A350
Beschreibung:
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1980R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1980R-A488
Lokale Artikelnummer::
BOSSBS-1980R-A488
Beschreibung:
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9207R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9207R-A350
Lokale Artikelnummer::
BOSSBS-9207R-A350
Beschreibung:
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9207R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9207R-A555
Lokale Artikelnummer::
BOSSBS-9207R-A555
Beschreibung:
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1980R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1980R-A647
Lokale Artikelnummer::
BOSSBS-1980R-A647
Beschreibung:
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5089R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5089R-A555
Lokale Artikelnummer::
BOSSBS-5089R-A555
Beschreibung:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5089R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5089R-A488
Lokale Artikelnummer::
BOSSBS-5089R-A488
Beschreibung:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7836R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7836R-A647
Lokale Artikelnummer::
BOSSBS-7836R-A647
Beschreibung:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7836R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7836R-HRP
Lokale Artikelnummer::
BOSSBS-7836R-HRP
Beschreibung:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0985R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0985R-A488
Lokale Artikelnummer::
BOSSBS-0985R-A488
Beschreibung:
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4736R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4736R-A750
Lokale Artikelnummer::
BOSSBS-4736R-A750
Beschreibung:
Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12527R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12527R
Lokale Artikelnummer::
BOSSBS-12527R
Beschreibung:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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