Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BLDPBD303666-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD303666-250MG
Lokale Artikelnummer::
BLDPBD303666-250MG
Beschreibung:
5-tert-Butyl 2-ethyl 6,7-dihydrofuro[3,2-c]pyridine-2,5(4H)-dicarboxylate 95+%
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-6992R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6992R-CY5
Lokale Artikelnummer::
BOSSBS-6992R-CY5
Beschreibung:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC300769-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC300769-1G
Lokale Artikelnummer::
APOSPC300769-1G
Beschreibung:
2-[2-(6-Fluoroimidazo[1,2-a]pyridin-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione hydrobromide
VE:
1 * 1 g
Artikel-Nr:
(F792-01)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKRF792-01
Beschreibung:
Coomassie® Brillantblau R 250, Laborreagens, J.T.Baker®
VE:
1 * 5 g
Lieferant:
VWR Chemicals
Beschreibung:
Coomassie Brillantblau G 250, Proteomik-Qualität
Artikel-Nr:
(APOSOR310410-500MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR310410-500MG
Lokale Artikelnummer::
APOSOR310410-500MG
Beschreibung:
2-Ethyl 5-(4-nitrophenyl)methyl 4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-2,5-dicarboxylate
VE:
1 * 500 mg
Artikel-Nr:
(BOSSBS-4100R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4100R-A680
Lokale Artikelnummer::
BOSSBS-4100R-A680
Beschreibung:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(9214-03)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR9214-03
Beschreibung:
Ethylmethylketon ≥99,5% (durch GC), BAKER ANALYZED® HPLC für die HPLC, UHPLC, für die Spektrophotometrie, J.T.Baker®
VE:
1 * 4 L
Artikel-Nr:
(BOSSBS-6073R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6073R-A350
Lokale Artikelnummer::
BOSSBS-6073R-A350
Beschreibung:
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6073R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6073R-A647
Lokale Artikelnummer::
BOSSBS-6073R-A647
Beschreibung:
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11773R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11773R-HRP
Lokale Artikelnummer::
BOSSBS-11773R-HRP
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-20187R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-20187R-A750
Lokale Artikelnummer::
BOSSBS-20187R-A750
Beschreibung:
Membrane-cytoskeleton-associated protein with F-actin-binding activity that induces F-actin bundles formation and stabilisation. Its F-actin-bundling activity is reversibly regulated upon its phosphorylation by the cAMP-dependent protein kinase A (PKA). Binds to the erythrocyte membrane glucose transporter-1 SLC2A1/GLUT1, and hence stabilises and attaches the spectrin-actin network to the erythrocytic plasma membrane. Plays a role in maintaining the functional integrity of PKA-activated erythrocyte shape and the membrane mechanical properties. Plays also a role as a modulator of actin dynamics in fibroblasts; acts as a negative regulator of the RhoA activation pathway. In platelets, functions as a regulator of internal calcium mobilisation across the dense tubular system that affects platelet granule secretion pathways and aggregation. Also required for the formation of a diverse set of cell protrusions, such as filopodia and lamellipodia, necessary for platelet cell spreading, motility and migration. Acts as a tumor suppressor and inhibits malignant cell transformation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11209R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11209R-A555
Lokale Artikelnummer::
BOSSBS-11209R-A555
Beschreibung:
Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A). Required for the proper formation of hair follicles and the control of epidermal differentiation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11722R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11722R-CY7
Lokale Artikelnummer::
BOSSBS-11722R-CY7
Beschreibung:
Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin ?1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome; a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt抯 lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11209R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11209R-A488
Lokale Artikelnummer::
BOSSBS-11209R-A488
Beschreibung:
Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A). Required for the proper formation of hair follicles and the control of epidermal differentiation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC3492-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC3492-1G
Lokale Artikelnummer::
APOSPC3492-1G
Beschreibung:
2-Brom-N-ethyl-4-(trifluormethoxy)benzolsulfonamid
VE:
1 * 1 g
Preis auf Anfrage
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