Suche >
IGEPAL\\\\\\\\u00AE+CA-630
Drucken
Sie suchten nach:
26 347 results were found
IGEPAL\\\\\\\\u00AE+CA-630
Artikel-Nr:
(BOSSBS-11765R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11765R-A750
Lokale Artikelnummer::
BOSSBS-11765R-A750
Beschreibung:
Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XIV, also known as SytXIV, is a 555 amino acid single-pass type III membrane protein belonging to the Synaptotagmin family. With the ability to form heterodimers, Synaptotagmin XIV mainly exists as a homodimer and contains two C2 domains, an N-terminal transmembrane domain and a putative fatty-acylation site. Synaptotagmin XIV is Ca²⁺ independent and may function in the trafficking and exocytosis of secretory vesicles to tissues outside the brain. Disruption of Synaptotagmin XIV may be affiliated with neurodevelopmental abnormalities. Synaptotagmin XIV exists as six alternatively spliced isoforms and is encoded by a gene on human chromosome 1q32.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1769R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1769R-A555
Lokale Artikelnummer::
BOSSBS-1769R-A555
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11765R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11765R-A680
Lokale Artikelnummer::
BOSSBS-11765R-A680
Beschreibung:
Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XIV, also known as SytXIV, is a 555 amino acid single-pass type III membrane protein belonging to the Synaptotagmin family. With the ability to form heterodimers, Synaptotagmin XIV mainly exists as a homodimer and contains two C2 domains, an N-terminal transmembrane domain and a putative fatty-acylation site. Synaptotagmin XIV is Ca²⁺ independent and may function in the trafficking and exocytosis of secretory vesicles to tissues outside the brain. Disruption of Synaptotagmin XIV may be affiliated with neurodevelopmental abnormalities. Synaptotagmin XIV exists as six alternatively spliced isoforms and is encoded by a gene on human chromosome 1q32.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1769R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1769R-A350
Lokale Artikelnummer::
BOSSBS-1769R-A350
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL21223-1KG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
21223-1KG
Lokale Artikelnummer::
SIAL21223-1KG
Beschreibung:
Hydroxylapatit ≥90% (as Ca3(PO4)2, KT), purum p.a., Sigma-Aldrich®
VE:
1 * 1 kg
Artikel-Nr:
(BOSSBS-13633R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13633R-A647
Lokale Artikelnummer::
BOSSBS-13633R-A647
Beschreibung:
The downstream of kinase family (Dok1-7) are members of a class of “docking†proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) — recessively inherited disorders characterized by muscle weakness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12478R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12478R-A680
Lokale Artikelnummer::
BOSSBS-12478R-A680
Beschreibung:
The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca²⁺ dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13633R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13633R-A750
Lokale Artikelnummer::
BOSSBS-13633R-A750
Beschreibung:
The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL04238-1KG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
04238-1KG
Lokale Artikelnummer::
SIAL04238-1KG
Beschreibung:
Hydroxylapatit ≥90% (berechnet auf leuchtenden Substanzen), puriss., erfüllt analytische Spezifikationen von Ph. Eur., BP, FCC, E341, Sigma-Aldrich®
VE:
1 * 1 kg
Artikel-Nr:
(BOSSBS-11196R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11196R-CY5
Lokale Artikelnummer::
BOSSBS-11196R-CY5
Beschreibung:
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function. R-cadherin (for retinal-cadherin, also designated cadherin-4), which was first identified in the retina of chicken, has been shown to be involved in the development of striated muscle and potentially epithelia in addition to its involvement in retinal development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7115R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7115R-A555
Lokale Artikelnummer::
BOSSBS-7115R-A555
Beschreibung:
MLC1 is a 377 amino acid multi-pass membrane protein that may serve as a non-selective neuronal cation channel in brain. Mutant MLC1 proteins that show impaired folding have been corrected in vitro with the addition of a Ca(2+)-ATPase inhibitor, curcumin. Mutations in the gene encoding MLC1 is the cause of megalencephalic leukoencephalopathy with subcortical cysts, also known as van der Knaap disease, a rare syndrome characterized early in life by progressive brain destruction causing mental retardation and incoordination. Single nucleotide polymorphisms within the MLC1 gene may be associated with periodic catatonia, but there seems to be conflicting evidence on whether or not the gene is implicated in general schizophrenia.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Calciumnitrat Tetrahydrat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Calciumnitrat Tetrahydrat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-13633R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13633R-FITC
Lokale Artikelnummer::
BOSSBS-13633R-FITC
Beschreibung:
The downstream of kinase family (Dok1-7) are members of a class of “docking†proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) — recessively inherited disorders characterized by muscle weakness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13633R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13633R-HRP
Lokale Artikelnummer::
BOSSBS-13633R-HRP
Beschreibung:
The downstream of kinase family (Dok1-7) are members of a class of “docking†proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) — recessively inherited disorders characterized by muscle weakness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5422R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5422R-A750
Lokale Artikelnummer::
BOSSBS-5422R-A750
Beschreibung:
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II.PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
