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IGEPAL\\\\\\\\u00AE+CA-630
Artikel-Nr:
(BOSSBS-11525R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11525R-HRP
Lokale Artikelnummer::
BOSSBS-11525R-HRP
Beschreibung:
MICAL1 is a 1,067 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one LIM zinc-binding domain and one calponin-homology domain. Expressed in kidney, thymus, spleen, lung and testis, MICAL1 interacts with the SH3 domain of Cas-L and, via this interaction, is thought to function as a cytoskeletal regulator that connects Cas-L to intermediate filaments. MICAL1 also interacts with Rab 1B, plexin-A3 and Vimentin, further regulating cytoskeletal events and possibly playing a role in axonal repulsion. Three isoforms of MICAL1 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-CY3
Lokale Artikelnummer::
BOSSBS-6425R-CY3
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 17553-86-5
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 2611-82-7
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 4244-84-2
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 102308-32-7
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 1139-30-6
Artikel-Nr:
(ACRO328540500)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
328540500
Lokale Artikelnummer::
ACRO328540500
Beschreibung:
CAS No.: 129-46-4
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-1589R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1589R-A555
Lokale Artikelnummer::
BOSSBS-1589R-A555
Beschreibung:
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1589R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1589R-A647
Lokale Artikelnummer::
BOSSBS-1589R-A647
Beschreibung:
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11983R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11983R-A647
Lokale Artikelnummer::
BOSSBS-11983R-A647
Beschreibung:
Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 37031-30-4
Artikel-Nr:
(BOSSBS-2082R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2082R-CY5.5
Lokale Artikelnummer::
BOSSBS-2082R-CY5.5
Beschreibung:
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2082R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2082R-CY7
Lokale Artikelnummer::
BOSSBS-2082R-CY7
Beschreibung:
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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