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L(-)-Glutathion+(oxidierte+Form)
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L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-8542R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8542R-CY7
Lokale Artikelnummer::
BOSSBS-8542R-CY7
Beschreibung:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5186R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5186R-A488
Lokale Artikelnummer::
BOSSBS-5186R-A488
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5186R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5186R-A647
Lokale Artikelnummer::
BOSSBS-5186R-A647
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0300R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0300R-CY5.5
Lokale Artikelnummer::
BOSSBS-0300R-CY5.5
Beschreibung:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5069R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5069R-A555
Lokale Artikelnummer::
BOSSBS-5069R-A555
Beschreibung:
This enzyme condenses acetyl CoA with acetoacetyl CoA to form HMG CoA, which is the substrate for HMG CoA reductase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8300R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8300R
Lokale Artikelnummer::
BOSSBS-8300R
Beschreibung:
Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8300R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8300R-A680
Lokale Artikelnummer::
BOSSBS-8300R-A680
Beschreibung:
Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidised to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidised to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidised Prx can be reduced back to the active form during recovery after oxidative stress.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3815R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3815R-CY3
Lokale Artikelnummer::
BOSSBS-3815R-CY3
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5885R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5885R-CY3
Lokale Artikelnummer::
BOSSBS-5885R-CY3
Beschreibung:
Myosin is a protein which is known to interact with actin in muscle and non-muscle cells. It contains two identical heavy chains and four light chains. Myosin molecules consist of two major regions: tails (rods) and heads. They aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. They are designated at type I (slow twitch) and type II (fast twitch).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6249R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6249R-A750
Lokale Artikelnummer::
BOSSBS-6249R-A750
Beschreibung:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9091R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9091R-CY3
Lokale Artikelnummer::
BOSSBS-9091R-CY3
Beschreibung:
Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleous.
VE:
1 * 100 µl
Artikel-Nr:
(BRDY170851)
Lieferant:
Brady
Hersteller-Artikelnummer::
170851
Lokale Artikelnummer::
BRDY170851
Beschreibung:
Tag a variety of assets with this tough polyethylene tag label material (B-145) that prints on both sides and folds to form an oval tag. Easily print anywhere with a Brady handheld label printer.
VE:
1 * 65 ST
Artikel-Nr:
(BOSSBS-0112R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0112R-A750
Lokale Artikelnummer::
BOSSBS-0112R-A750
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8248R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8248R-A488
Lokale Artikelnummer::
BOSSBS-8248R-A488
Beschreibung:
May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9575R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9575R-CY3
Lokale Artikelnummer::
BOSSBS-9575R-CY3
Beschreibung:
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0347R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0347R-CY5
Lokale Artikelnummer::
BOSSBS-0347R-CY5
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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