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L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-0417R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0417R-FITC
Lokale Artikelnummer::
BOSSBS-0417R-FITC
Beschreibung:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8329R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8329R-HRP
Lokale Artikelnummer::
BOSSBS-8329R-HRP
Beschreibung:
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5105R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5105R-FITC
Lokale Artikelnummer::
BOSSBS-5105R-FITC
Beschreibung:
PRE7 is a subunit of the Yeast proteasome. The yeast proteasome seems to be composed of 14 different subunits which form a highly ordered ring-shaped structure. The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4215R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4215R-FITC
Lokale Artikelnummer::
BOSSBS-4215R-FITC
Beschreibung:
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13198R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13198R
Lokale Artikelnummer::
BOSSBS-13198R
Beschreibung:
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2158R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-A647
Lokale Artikelnummer::
BOSSBS-2158R-A647
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2158R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-A750
Lokale Artikelnummer::
BOSSBS-2158R-A750
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12141R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12141R-A488
Lokale Artikelnummer::
BOSSBS-12141R-A488
Beschreibung:
LRFN1 is a 771 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing a fibronectin type-III domain, an Ig-like (immunoglobulin-like) domain, a LRRCT domain, a LRRNT domain and seven LRR (leucine-rich) repeats, LRFN1 is thought to promote neurite outgrowth in hippocampal neurons and is involved in the regulation and maintenance of excitatory synapses. LRFN1 forms heteromeric complexes with LRFN2, LRFN3, LFRN4 and LFRN5, but does not have the ability to form homomeric complexes across cell junctions of adjacent cells like other LRFN family members. The PDZ-binding motif of LRFN1 is required for neurite outgrowth promotion and for SAP 97-, NE-dlg- and PSD-95-binding. LRFN1 is encoded by a gene located on human chromosome 19q13.2 and mouse chromosome 7 A3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13198R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13198R-A647
Lokale Artikelnummer::
BOSSBS-13198R-A647
Beschreibung:
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2158R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-FITC
Lokale Artikelnummer::
BOSSBS-2158R-FITC
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12949R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12949R-CY3
Lokale Artikelnummer::
BOSSBS-12949R-CY3
Beschreibung:
CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9345R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9345R
Lokale Artikelnummer::
BOSSBS-9345R
Beschreibung:
E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.
VE:
1 * 100 µl
Lieferant:
Bohlender
Beschreibung:
b.safe Kappen mit Fittings, Kapillaren und Belüftungsventil als perfekte Einheit zum Extrahieren von Lösungsmitteln aus Laborbehältern.
Artikel-Nr:
(LIOF612401)
Lieferant:
LIOFILCHEM
Hersteller-Artikelnummer::
612401
Lokale Artikelnummer::
LIOF612401
Beschreibung:
Natriumdesoxycholat ist das Natriumsalz der Desoxycholsäure, einer hochgereinigten Gallensäure, und hemmt grampositive Kokken und sporenbildende Organismen. Nährmedien, die Natriumdesoxycholat enthalten, werden zur Zählung von Coliformen aus Milch, Wasser, Abwasser usw. und zur Isolierung von Darmpathogenen verwendet.
VE:
1 * 500 g
New Product
Artikel-Nr:
(BOSSBS-12414R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12414R-A350
Lokale Artikelnummer::
BOSSBS-12414R-A350
Beschreibung:
MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13198R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13198R-CY3
Lokale Artikelnummer::
BOSSBS-13198R-CY3
Beschreibung:
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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