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2-Methoxypyrimidine-5-carbonitrile
Artikel-Nr:
(BOSSBS-0163R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0163R-CY3
Lokale Artikelnummer::
BOSSBS-0163R-CY3
Beschreibung:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1815R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1815R-A750
Lokale Artikelnummer::
BOSSBS-1815R-A750
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12910R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12910R-HRP
Lokale Artikelnummer::
BOSSBS-12910R-HRP
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3665R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3665R-A647
Lokale Artikelnummer::
BOSSBS-3665R-A647
Beschreibung:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].The antibody should recognize both pro-form and p20 cleaved-form. The antibody does not cross-react with other Caspase family members.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3665R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3665R-HRP
Lokale Artikelnummer::
BOSSBS-3665R-HRP
Beschreibung:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].The antibody should recognize both pro-form and p20 cleaved-form. The antibody does not cross-react with other Caspase family members.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6716R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6716R-CY5
Lokale Artikelnummer::
BOSSBS-6716R-CY5
Beschreibung:
Uricase catalyzes the oxidation of uric acid to 5 hydroxyisourate which spontaneously decomposes to form allantoin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1815R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1815R-A555
Lokale Artikelnummer::
BOSSBS-1815R-A555
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1815R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1815R-A488
Lokale Artikelnummer::
BOSSBS-1815R-A488
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3334R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3334R-A680
Lokale Artikelnummer::
BOSSBS-3334R-A680
Beschreibung:
Glycolytic enzyme that catalyses the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3334R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3334R-A647
Lokale Artikelnummer::
BOSSBS-3334R-A647
Beschreibung:
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0101R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0101R-FITC
Lokale Artikelnummer::
BOSSBS-0101R-FITC
Beschreibung:
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
VE:
1 * 100 µl
Lieferant:
Ludwig Schneider GmbH & CO. KG
Beschreibung:
These thermometers are used for block thermostats, supplied in a plastic reaction tube, filled with 1 ml mineral oil.
Lieferant:
BARNSTEAD THERMOLYNE
Beschreibung:
Klemme für Schüttler, Klemme für 2500-ml-Kulturflasche mit niedriger Form, Für: 1 (280×330); 1 (457×457); 2 (457×609) für MaxQ 2000 3 (760×457) und 6 (910×609) Klemmen für MaxQ 3000
Artikel-Nr:
(BOSSBS-3154R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3154R-A750
Lokale Artikelnummer::
BOSSBS-3154R-A750
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3154R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3154R-A488
Lokale Artikelnummer::
BOSSBS-3154R-A488
Beschreibung:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8300R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8300R-A350
Lokale Artikelnummer::
BOSSBS-8300R-A350
Beschreibung:
Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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