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Tris(2,2,2-trifluoroethyl)+Phosphate
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Tris(2,2,2-trifluoroethyl)+Phosphate
Artikel-Nr:
(PRSI92-658)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-658
Lokale Artikelnummer::
PRSI92-658
Beschreibung:
Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-0638R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0638R-A680
Lokale Artikelnummer::
BOSSBS-0638R-A680
Beschreibung:
Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI76-381)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-381
Lokale Artikelnummer::
PRSI76-381
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI76-375)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-375
Lokale Artikelnummer::
PRSI76-375
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,1 mg
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
EDTA (Ethylendiamintetraessigsäure), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Gentamicinsulfat, Sigma-Aldrich®
Artikel-Nr:
(PROOSPS-SW2)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
SPS-SW2
Lokale Artikelnummer::
PROOSPS-SW2
Beschreibung:
This reference standard is intended for daily use in conjunction with measurement of elements in surface waters. The water solution contains 45 elements with concentrations traceable to
ultrapure metals or stoichiometrically well-defined substances.
VE:
1 * 6 ST
Artikel-Nr:
(PRSI76-351)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-351
Lokale Artikelnummer::
PRSI76-351
Beschreibung:
The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI76-334)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-334
Lokale Artikelnummer::
PRSI76-334
Beschreibung:
The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(PRSI76-380)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-380
Lokale Artikelnummer::
PRSI76-380
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI76-379)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-379
Lokale Artikelnummer::
PRSI76-379
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI76-346)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-346
Lokale Artikelnummer::
PRSI76-346
Beschreibung:
The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI91-282)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-282
Lokale Artikelnummer::
PRSI91-282
Beschreibung:
Activin proteins that belong to the transforming growth factor-beta (TGF- beta ) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.
VE:
1 * 50 µG
Artikel-Nr:
(REST32004)
Lieferant:
Restek
Hersteller-Artikelnummer::
32004
Lokale Artikelnummer::
REST32004
Beschreibung:
Organic Standard, Pesticide standard mix B with surrogates includes aldrin, endosulfan II, β-BHC, endosulfan sulphate, δ-BHC, endrin aldehyde, α-chlordane, endrin ketone, γ-chlordane, heptachlor epoxide (isomer B), 4,4'-DDE, 2,4,5,6-tetrachloro-m-xylene (SS), decachlorobiphenyl (SS), in hexane, 1 ml/ampoule
VE:
1 * 1 mL
Artikel-Nr:
(PRSI76-339)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-339
Lokale Artikelnummer::
PRSI76-339
Beschreibung:
The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(KRAF03036.1000)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
03036.1000
Lokale Artikelnummer::
KRAF03036.1000
Beschreibung:
Neßler-Reagenz
VE:
1 * 250 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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