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2-(Diethylamino)benzonitrile
Artikel-Nr:
(BOSSBS-8160R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8160R-A680
Lokale Artikelnummer::
BOSSBS-8160R-A680
Beschreibung:
GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3382R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3382R-A680
Lokale Artikelnummer::
BOSSBS-3382R-A680
Beschreibung:
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2806R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2806R-FITC
Lokale Artikelnummer::
BOSSBS-2806R-FITC
Beschreibung:
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2806R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2806R-A555
Lokale Artikelnummer::
BOSSBS-2806R-A555
Beschreibung:
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(91120.001)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC91120.001
Beschreibung:
A standard mixture, typically used for food testing, containing the following components: 100 ug/ml each of Bromfenvinphos-methyl [CAS:13104-21-7] ; Bromfenvinfos [CAS:33399-00-7] ; Bromophos-ethyl [CAS:4824-78-6] ; Bromophos-methyl [CAS:2104-96-3] ; Carbophenothion [CAS:786-19-6] ; Chlorfenvinphos [CAS:470-90-6] ; Chlorthiophos [CAS:60238-56-4] ; Coumaphos [CAS:56-72-4] ; Edifenphos [CAS:17109-49-8] ; Ethion [CAS:563-12-2] ; Fenamiphos [CAS:22224-92-6] ; Fenchlorphos [CAS:299-84-3] ; Fenthion [CAS:55-38-9] ; Iodofenphos [CAS:18181-70-9] ; Leptophos [CAS:21609-90-5] ; Malathion [CAS:121-75-5] ; Methacrifos [CAS:62610-77-9] ; Profenofos [CAS:41198-08-7] ; Prothiophos [CAS:34643-46-4] ; Sulfotep [CAS:3689-24-5] ; Sulprofos [CAS:35400-43-2] ; Terbufos [CAS:13071-79-9] ; cis-Tetrachlorvinphos [CAS:22248-79-9] ; Tolclofos-methyl [CAS:57018-04-9] in Toluene
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-3382R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3382R-CY3
Lokale Artikelnummer::
BOSSBS-3382R-CY3
Beschreibung:
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3382R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3382R-CY5
Lokale Artikelnummer::
BOSSBS-3382R-CY5
Beschreibung:
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13731R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13731R-CY7
Lokale Artikelnummer::
BOSSBS-13731R-CY7
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH21 (protocadherin 21), also known as PRCAD, is an 859 amino acid single-pass membrane protein that localizes to the outer segments of photoreceptor cells and contains six cadherin domains. Existing as multiple alternatively spliced isoforms, PCDH21 functions as a calcium-dependent cell adhesion protein that is thought to be required for the structural integrity of photoreceptor cells and may be involved in the formation and maintenance of neuronal networks.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13731R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13731R-CY5
Lokale Artikelnummer::
BOSSBS-13731R-CY5
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH21 (protocadherin 21), also known as PRCAD, is an 859 amino acid single-pass membrane protein that localizes to the outer segments of photoreceptor cells and contains six cadherin domains. Existing as multiple alternatively spliced isoforms, PCDH21 functions as a calcium-dependent cell adhesion protein that is thought to be required for the structural integrity of photoreceptor cells and may be involved in the formation and maintenance of neuronal networks.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2605R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2605R-CY3
Lokale Artikelnummer::
BOSSBS-2605R-CY3
Beschreibung:
IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5843R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5843R-A555
Lokale Artikelnummer::
BOSSBS-5843R-A555
Beschreibung:
PCDHB11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5843R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5843R-CY7
Lokale Artikelnummer::
BOSSBS-5843R-CY7
Beschreibung:
PCDHB11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15502R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15502R
Lokale Artikelnummer::
BOSSBS-15502R
Beschreibung:
RGS14 is a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3933R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3933R-CY5.5
Lokale Artikelnummer::
BOSSBS-3933R-CY5.5
Beschreibung:
Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3933R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3933R-CY5
Lokale Artikelnummer::
BOSSBS-3933R-CY5
Beschreibung:
Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15538R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15538R-CY3
Lokale Artikelnummer::
BOSSBS-15538R-CY3
Beschreibung:
Isocitrate dehydrogenases catalyse the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilises NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localise to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyse the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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