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Artikel-Nr:
(BOSSBS-4250R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4250R-FITC
Lokale Artikelnummer::
BOSSBS-4250R-FITC
Beschreibung:
The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6073R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6073R-CY7
Lokale Artikelnummer::
BOSSBS-6073R-CY7
Beschreibung:
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4250R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4250R-A680
Lokale Artikelnummer::
BOSSBS-4250R-A680
Beschreibung:
The three dimensional structure of many extracellular proteins is stabilised by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4250R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4250R-HRP
Lokale Artikelnummer::
BOSSBS-4250R-HRP
Beschreibung:
The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1927R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1927R-CY7
Lokale Artikelnummer::
BOSSBS-1927R-CY7
Beschreibung:
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8512R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8512R-A555
Lokale Artikelnummer::
BOSSBS-8512R-A555
Beschreibung:
Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11496R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11496R-HRP
Lokale Artikelnummer::
BOSSBS-11496R-HRP
Beschreibung:
Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8512R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8512R-A488
Lokale Artikelnummer::
BOSSBS-8512R-A488
Beschreibung:
Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8512R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8512R-A647
Lokale Artikelnummer::
BOSSBS-8512R-A647
Beschreibung:
Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12106R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12106R-FITC
Lokale Artikelnummer::
BOSSBS-12106R-FITC
Beschreibung:
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5581R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5581R-FITC
Lokale Artikelnummer::
BOSSBS-5581R-FITC
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4159R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4159R-FITC
Lokale Artikelnummer::
BOSSBS-4159R-FITC
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4159R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4159R-A488
Lokale Artikelnummer::
BOSSBS-4159R-A488
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5581R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5581R-HRP
Lokale Artikelnummer::
BOSSBS-5581R-HRP
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12106R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12106R-A350
Lokale Artikelnummer::
BOSSBS-12106R-A350
Beschreibung:
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4054R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4054R-A647
Lokale Artikelnummer::
BOSSBS-4054R-A647
Beschreibung:
S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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