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tert-Butyl+2-amino-4-(trifluoromethyl)benzoate
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tert-Butyl+2-amino-4-(trifluoromethyl)benzoate
Artikel-Nr:
(BOSSBS-1026R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1026R
Lokale Artikelnummer::
BOSSBS-1026R
Beschreibung:
Anti-DES Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15279R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15279R-A680
Lokale Artikelnummer::
BOSSBS-15279R-A680
Beschreibung:
Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf64 gene product has been provisionally designated C7orf64 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6119R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6119R-A750
Lokale Artikelnummer::
BOSSBS-6119R-A750
Beschreibung:
May be involved in the regulation of cellular proliferation and/or differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15487R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15487R-A488
Lokale Artikelnummer::
BOSSBS-15487R-A488
Beschreibung:
HIF Prolyl Hydroxylases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15237R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15237R-CY5
Lokale Artikelnummer::
BOSSBS-15237R-CY5
Beschreibung:
Making up nearly 6% of the human genome, chromosome 6 contains around 1200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf203 gene product has been provisionally designated C6orf203 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13490R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13490R-HRP
Lokale Artikelnummer::
BOSSBS-13490R-HRP
Beschreibung:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reticulum and assist in the transport of protein cargo through the Golgi apparatus. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3709R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3709R-CY5.5
Lokale Artikelnummer::
BOSSBS-3709R-CY5.5
Beschreibung:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2483R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2483R-A350
Lokale Artikelnummer::
BOSSBS-2483R-A350
Beschreibung:
Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13367R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13367R-A350
Lokale Artikelnummer::
BOSSBS-13367R-A350
Beschreibung:
This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3930R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3930R-FITC
Lokale Artikelnummer::
BOSSBS-3930R-FITC
Beschreibung:
Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10446R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10446R-FITC
Lokale Artikelnummer::
BOSSBS-10446R-FITC
Beschreibung:
Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1336R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1336R-A555
Lokale Artikelnummer::
BOSSBS-1336R-A555
Beschreibung:
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F() activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11326R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11326R-A750
Lokale Artikelnummer::
BOSSBS-11326R-A750
Beschreibung:
Probable regulator of calmodulin Signalling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3408R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3408R-A750
Lokale Artikelnummer::
BOSSBS-3408R-A750
Beschreibung:
KAT13B/AIB1 interacts in a ligand-dependent fashion with the oestrogen receptor to enhance oestrogen-dependent transcriptional gene activation. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits KAT3A / KAT3B as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7115R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7115R-CY7
Lokale Artikelnummer::
BOSSBS-7115R-CY7
Beschreibung:
MLC1 is a 377 amino acid multi-pass membrane protein that may serve as a non-selective neuronal cation channel in brain. Mutant MLC1 proteins that show impaired folding have been corrected in vitro with the addition of a Ca(2+)-ATPase inhibitor, curcumin. Mutations in the gene encoding MLC1 is the cause of megalencephalic leukoencephalopathy with subcortical cysts, also known as van der Knaap disease, a rare syndrome characterized early in life by progressive brain destruction causing mental retardation and incoordination. Single nucleotide polymorphisms within the MLC1 gene may be associated with periodic catatonia, but there seems to be conflicting evidence on whether or not the gene is implicated in general schizophrenia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9376R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9376R-A647
Lokale Artikelnummer::
BOSSBS-9376R-A647
Beschreibung:
MuRF1, is a nuclear protein that interacts with SMT3b and the large myofibrillar protein Titin. In muscle cells, MuRF2 (RFN29) regulates gene expression and protein turnover. It localizes to the cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2 can form oligomers with various other proteins, including Titin and Myosin. MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. MuRF3 shares 77% and 65% sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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