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3-(4-Fluorophenyl)oxetan-3-ol
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3-(4-Fluorophenyl)oxetan-3-ol
Artikel-Nr:
(BOSSBS-2510R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2510R-A555
Lokale Artikelnummer::
BOSSBS-2510R-A555
Beschreibung:
ZNF217 (Zinc-finger protein 217) is a Kruppel-like zinc-finger protein which functions as a transcriptional repressor protein and forms a complex with a number of proteins including CoREST, BHC110/LSD1, HDAC2 and CtBP1. ZNF217 has been shown to repress E-cadherin promoter activity. ZNF217 is overexpressed in a number of cancers including breast and ovarian. ZNF217 and its associated proteins have been implicated in a novel pathway that is involved in cancer progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10369R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10369R-A555
Lokale Artikelnummer::
BOSSBS-10369R-A555
Beschreibung:
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5204R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5204R-A680
Lokale Artikelnummer::
BOSSBS-5204R-A680
Beschreibung:
E2-like enzyme involved in autophagy and mitochondrial homeostasis. catalyses the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R-CY7
Lokale Artikelnummer::
BOSSBS-3349R-CY7
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10400R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10400R-A647
Lokale Artikelnummer::
BOSSBS-10400R-A647
Beschreibung:
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11024R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11024R-A680
Lokale Artikelnummer::
BOSSBS-11024R-A680
Beschreibung:
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5204R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5204R-CY5
Lokale Artikelnummer::
BOSSBS-5204R-CY5
Beschreibung:
E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1638R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1638R-A350
Lokale Artikelnummer::
BOSSBS-1638R-A350
Beschreibung:
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R
Lokale Artikelnummer::
BOSSBS-3349R
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2931R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2931R-A488
Lokale Artikelnummer::
BOSSBS-2931R-A488
Beschreibung:
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5094R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5094R-CY7
Lokale Artikelnummer::
BOSSBS-5094R-CY7
Beschreibung:
UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria. Porphyria cutanea tarda is an autosomal dominant disorder characterized by light-sensitive dermatitis and associated with the excretion of large amounts of uroporphyrin in urine. Hepatoerythropoetic porphyria is a form of porphyria cutanae tarda that may also be a manifestation of benign or malignant hepatic tumors.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Fibronectin is a dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.
Artikel-Nr:
(BOSSBS-3802R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3802R-A750
Lokale Artikelnummer::
BOSSBS-3802R-A750
Beschreibung:
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R-CY5
Lokale Artikelnummer::
BOSSBS-3349R-CY5
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3793R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3793R-A750
Lokale Artikelnummer::
BOSSBS-3793R-A750
Beschreibung:
The protein encoded by this gene is a type II membrane protein that catalyses the transfer of sialic acid from CMP sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi apparatus but which can be proteolytically processed to a soluble form, is involved in the generation of the cell surface carbohydrate determinants and differentiation antigens HB6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4684R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4684R-CY3
Lokale Artikelnummer::
BOSSBS-4684R-CY3
Beschreibung:
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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