1-(3-Aminopropyl)pyrrolidin
Lieferant:
Tonbo Biosciences
Beschreibung:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). These receptors are expressed by B cells, monocytes, macrophages, NK cells, dendritic cells, and neutrophils.
Artikel-Nr:
(BOSSBS-6735R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6735R-HRP
Lokale Artikelnummer::
BOSSBS-6735R-HRP
Beschreibung:
SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13591R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13591R-CY3
Lokale Artikelnummer::
BOSSBS-13591R-CY3
Beschreibung:
Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2646R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2646R-CY5
Lokale Artikelnummer::
BOSSBS-2646R-CY5
Beschreibung:
Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6338R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6338R-CY3
Lokale Artikelnummer::
BOSSBS-6338R-CY3
Beschreibung:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
VE:
1 * 100 µl
Artikel-Nr:
(USBI125306)
Lieferant:
US Biological
Hersteller-Artikelnummer::
125306
Lokale Artikelnummer::
USBI125306
Beschreibung:
Anti-CRABP2 Mouse Monoclonal Antibody [clone: 4F2]
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-5036R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5036R-FITC
Lokale Artikelnummer::
BOSSBS-5036R-FITC
Beschreibung:
Apolipoprotein C-II (apoCII) is in found in chylomicrons (large lipoprotein particles absorbed from the gastrointestinal tract) and VLDL (large lipoproteins that are broken down to eventually form LDL). ApoCII activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7780R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7780R-A555
Lokale Artikelnummer::
BOSSBS-7780R-A555
Beschreibung:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
VE:
1 * 100 µl
Artikel-Nr:
(531-1108)
Lieferant:
IKA
Hersteller-Artikelnummer::
25003604
Lokale Artikelnummer::
IKAA25003604
Beschreibung:
Der Drehmomentmessrührer STARVISC 200-2.5 control ermittelt die Viskosität und zeigt das Ergebnis direkt auf dem Display an. Damit bietet der ein breites Einsatzspektrum.
VE:
1 * 1 ST
Artikel-Nr:
(USBIM3887-67A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
M3887-67A
Lokale Artikelnummer::
USBIM3887-67A
Beschreibung:
Anti-MHC Class 2, RT1B Mouse Monoclonal Antibody [clone: 10F145]
VE:
1 * 250 µG
Artikel-Nr:
(BOSSBS-2937R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2937R-A680
Lokale Artikelnummer::
BOSSBS-2937R-A680
Beschreibung:
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localises to the endoplasmic reticulum and the Golgi apparatus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3756R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3756R-A647
Lokale Artikelnummer::
BOSSBS-3756R-A647
Beschreibung:
PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3756R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3756R-A555
Lokale Artikelnummer::
BOSSBS-3756R-A555
Beschreibung:
PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4038R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4038R-A647
Lokale Artikelnummer::
BOSSBS-4038R-A647
Beschreibung:
SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-CY5
Lokale Artikelnummer::
BOSSBS-6076R-CY5
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4730R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4730R-A680
Lokale Artikelnummer::
BOSSBS-4730R-A680
Beschreibung:
Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in foetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
VE:
1 * 100 µl
Preis auf Anfrage
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