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2-Fluor-4-(pentafluorthio)benzamid
Artikel-Nr:
(USBI035009)
Lieferant:
US Biological
Hersteller-Artikelnummer::
035009
Lokale Artikelnummer::
USBI035009
Beschreibung:
Anti-EIF4A2 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI131073)
Lieferant:
US Biological
Hersteller-Artikelnummer::
131073
Lokale Artikelnummer::
USBI131073
Beschreibung:
Anti-PDHA2 Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBI150962)
Lieferant:
US Biological
Hersteller-Artikelnummer::
150962
Lokale Artikelnummer::
USBI150962
Beschreibung:
Anti-SET Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(SIAL318922-100ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
318922-100ML
Lokale Artikelnummer::
SIAL318922-100ML
Beschreibung:
Ferroin (1,10-Phenanthrolin-Eisen(II)sulfat-Komplex) 0,1% in wässriger Lösung Indikator
VE:
1 * 100 mL
Lieferant:
Sigma-Aldrich
Beschreibung:
Horseradish peroxidase, Typ II
Artikel-Nr:
(PRSI91-896)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-896
Lokale Artikelnummer::
PRSI91-896
Beschreibung:
Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.
VE:
1 * 50 µG
Artikel-Nr:
(USBI042684)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042684
Lokale Artikelnummer::
USBI042684
Beschreibung:
Anti-TCEAL1 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BNUM1208-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1208-50
Lokale Artikelnummer::
BTIUBNUM1208-50
Beschreibung:
This MAb reacts with the beta-chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
VE:
1 * 50 µl
Artikel-Nr:
(ABNOPAB16602)
Lieferant:
Abnova
Hersteller-Artikelnummer::
PAB16602
Lokale Artikelnummer::
ABNOPAB16602
Beschreibung:
Rabbit polyclonal antibody raised against synthetic peptides of Strep-tag II.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3477R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3477R-FITC
Lokale Artikelnummer::
BOSSBS-3477R-FITC
Beschreibung:
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
Artikel-Nr:
(BOSSBS-1930R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1930R
Lokale Artikelnummer::
BOSSBS-1930R
Beschreibung:
Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10438R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10438R-CY3
Lokale Artikelnummer::
BOSSBS-10438R-CY3
Beschreibung:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7772R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7772R-CY7
Lokale Artikelnummer::
BOSSBS-7772R-CY7
Beschreibung:
Septin 14, also known as SEPT14, is a 432 amino acid protein that belongs to the septin family. The highly conserved septin family of GTP-binding cytoskeletal proteins is implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis and other cellular functions. Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. Septin 14 has a GTPase domain followed by a C-terminal coiled-coil domain characteristic of group II septins. Septin 14 interacted with all septins except those that are members of its phylogenetic cluster, including itself. Septin 14 shares highest identity (67%) with Septin 10. Expressed in testis and more weakly in fetal liver, tonsil and thymus, the Septin 14 protein is not detected in testicular cancer or other normal or cancer cell lines. The Septin 14 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 7p11.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11073R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11073R-CY5
Lokale Artikelnummer::
BOSSBS-11073R-CY5
Beschreibung:
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis. EY-cadherin, also known as CDH18 (cadherin 18), CDH14 (cadherin 14), CDH24 or CDH14L, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains. One of several members of the cadherin superfamily, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), where it plays a role in cell-cell binding events. Specifically, EY-cadherin is thought to be involved in axon guidance and outgrowth, as well as synaptic adhesion within the CNS. EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, but lacks the HAV cell adhesion sequence that is specific to type I cadherins. The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, implicating EY-cadherin as a potential tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13273R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13273R-A750
Lokale Artikelnummer::
BOSSBS-13273R-A750
Beschreibung:
The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T1, also known as GALNT1 (Polypeptide N-acetylgalactosaminyltransferase 1), is a ubiquitously expressed 559 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and, like other GalNAc-Ts, contains a stem region and a C-terminal ricin/lectin-like domain. GalNAc-T1 catalyzes the first reaction in O-linked oligosaccharide biosynthesis, namely the transfer of an N-acetyl-D-galactosamine residue to a protein acceptor. GalNAc-T1 uses calcium and manganese as cofactors. Due to alternative splicing events, two GalNAc-T1 isoforms are expressed.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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