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Quecksilber(II)trifluormethansulfonat
Artikel-Nr:
(181-1084)
Lieferant:
VACUUBRAND
Hersteller-Artikelnummer::
20738100
Lokale Artikelnummer::
VACU20738100
Beschreibung:
Diese Membranpumpen kombinieren moderne Regelelektronik und -software mit leistungsfähiger Mechanik. Sie regeln das Vakuum punktgenau durch Anpassen der Drehzahl der Membranpumpe; sie ermöglichen ein automatisches Finden des Dampfdrucks und ein selbstständiges Anpassen des Vakuums an den Prozessverlauf. Die schnelle adaptive Regelung stellt, unabhängig von der Größe der Apparatur und der Menge des Gasanfalls, immer das angemessene Saugvermögen bereit. VARIO Membranpumpen bestehen immer aus der Pumpe, sowie dem Vakuum-Controller mit Anzeige und Vakuum-Sensor.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI76-325)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-325
Lokale Artikelnummer::
PRSI76-325
Beschreibung:
The OKT4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II). The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
VE:
1 * 100 Tests
New Product
Lieferant:
Alfa Aesar
Beschreibung:
Bariumperoxid, wasserfrei ≥84%, technische Qualität
Artikel-Nr:
(PRSI91-722)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-722
Lokale Artikelnummer::
PRSI91-722
Beschreibung:
Cadherin-8 (CDH8) is a type II classical cadherin from the cadherin superfamily. Member of the Cadherin superfamily are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. The extracellular domain of CDH8 contains five cadherin domains. CDH8 is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-032)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-032
Lokale Artikelnummer::
PRSI76-032
Beschreibung:
The FR70 monoclonal antibody specifically binds to mouse CD70, a 30 to 33 kDa type II transmembrane protein and member of the TNF superfamily. CD70 is the ligand for CD27 and is expressed on dendritic cells, activated B cell, and a subset of activated T cells at lower levels. Its main role is in regulating B cell activation and immunoglobulin synthesis. CD70 expressing cells are able to co-stimulate T cell proliferation and upregulate cytokine production. The FR70 antibody is reported to block the binding of CD70 to CD27.
VE:
1 * 0,05 mg
New Product
Artikel-Nr:
(PRSI76-579)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-579
Lokale Artikelnummer::
PRSI76-579
Beschreibung:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI5393)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5393
Lokale Artikelnummer::
PRSI5393
Beschreibung:
AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
VE:
1 * 100 µG
Artikel-Nr:
(181-0339)
Lieferant:
VACUUBRAND
Hersteller-Artikelnummer::
20696735
Lokale Artikelnummer::
VACU20696735
Beschreibung:
Die VARIO® Chemiepumpeneinheit stellt Vakuumkontrolle durch präzise und ständige Anpassung der Motordrehzahl der Membranpumpe bereit. Die Motordrehzahlregelung auf Anforderung verlängert die Lebensdauer der Membran beträchtlich.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI28-029)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-029
Lokale Artikelnummer::
PRSI28-029
Beschreibung:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
di-Silberoxid, Sigma-Aldrich®
Artikel-Nr:
(PRSIXPS-2018)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-2018
Lokale Artikelnummer::
PRSIXPS-2018
Beschreibung:
The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-106-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-106-100
Lokale Artikelnummer::
BSENR-106-100
Beschreibung:
The neural adhesion molecule Contactin-6, also known as NB-3, is a contactin/F3 subgroup member of immunoglobulin superfamily. It is expressed exclusively in the nervous system and mainly upregulated at the early postnatal stage during mouse brain development. Employing Northern blot analysis Kamei et al found that amongst different regions of the adult human nervous system cerebellum expressed highest level of NB-3 mRNA. The expression of NB-3 in the cerebellum increases until adulthood. In contrast, the expression in the cerebrum declines to a low level after postnatal day 7. NB-3 like other neural recognition molecules plays a vitally important role in axonal guidance during development, plasticity, and maintenance of synaptic connections in the adult brain. Cui et al recently showed that NB-3 acts as a novel Notch ligand to participate in oligodendrocyte generation. Furthermore, NB-3 triggers nuclear translocation of the Notch intracellular domain and promotes oligodendrogliogenesis from progenitor cells and differentiation of oligodendrocyte precursor cells via Deltex1. In primary oligodendrocytes, NB-3 increases myelin-associated glycoprotein transcripts. Hence, the NB-3/Notch signaling pathway may be worthwhile a closer examination for its potential for the treatment of demyelinating diseases. Human NB-3 shares with rat NB-3 86% identity in nucleotide sequences and 90% identity in amino acid sequences. FUNCTION: Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. SUBCELLULAR LOCATION: Cell membrane; lipid-anchor; GPI-anchor. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Expressed in brain. In brain, it is preferentially expressed in the accessory olfactory bulb, layers II/III and V of the cerebral cortex, piriform cortex, anterior thalamic nuclei, locus coeruleus of the pons and mesencephalic trigeminal nucleus and in Purkinje cells of the cerebellum.
VE:
1 * 100 µl
Lieferant:
BARNSTEAD THERMOLYNE
Beschreibung:
Count on the Thermo Scientific™ Aquanex™ Ultrapure water purification systems for convenience, flexibility and reliable water purity. With an intuitive touch screen interface and easy-access consumables, you can spend more time on your research and less time maintaining your equipment.
Artikel-Nr:
(PRSI30-089)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-089
Lokale Artikelnummer::
PRSI30-089
Beschreibung:
RXRB is a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-474)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-474
Lokale Artikelnummer::
PRSI90-474
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-478)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-478
Lokale Artikelnummer::
PRSI90-478
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
VE:
1 * 10 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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