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Soluble+gamma-cyclodextrin+polymer+crosslinked+with+epichlorohydr
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Lieferant:
MACRON AVANTOR BRAND
Beschreibung:
Kaliumdihydrogenphosphat ≥99,0% (durch Acidimetrie), Kristalle, AR® ACS, Macron Fine Chemicals™
Artikel-Nr:
(BOSSBS-11418R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11418R-A680
Lokale Artikelnummer::
BOSSBS-11418R-A680
Beschreibung:
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream Signalling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several Signalling cascades including the RAS-ERK, PI3 kinase-AKT, or PLC gamma-PKC. RON Signalling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11773R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11773R-A680
Lokale Artikelnummer::
BOSSBS-11773R-A680
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca²⁺ dependent enzymes, which catalyse the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyses the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3345R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3345R-A555
Lokale Artikelnummer::
BOSSBS-3345R-A555
Beschreibung:
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Phosphorylates NEDD1. NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation. Phosphorylates both ECT2 and RACGAP1, and thereby stimulates their interaction that is essential for the cleavage furrow formation. Promotes the central spindle recruitment of ECT2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11773R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11773R-A488
Lokale Artikelnummer::
BOSSBS-11773R-A488
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11773R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11773R-A350
Lokale Artikelnummer::
BOSSBS-11773R-A350
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13264R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13264R-A680
Lokale Artikelnummer::
BOSSBS-13264R-A680
Beschreibung:
There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9612R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9612R-A488
Lokale Artikelnummer::
BOSSBS-9612R-A488
Beschreibung:
PIBF is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells). In the presence of PIBF, natural killer (NK) cells inhibit the release of perforin from storage granules and therefore fail to lyse target cells. In humans, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF is associated with the nucleus, whereas secretion of shorter forms is induced by activation of the cell. Research suggests that PIBF functions as a transcription factor in its full-length form, while smaller forms may act as cytokines. The PIBF gene encodes a deduced hydrophilic 757-amino acid alpha-helical protein with an N-terminal signal sequence, a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an endoplasmic reticulum membrane retention signal, and many presumeed N-glycosylation and phosphorylation sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5828R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5828R-CY5
Lokale Artikelnummer::
BOSSBS-5828R-CY5
Beschreibung:
Cadherins are calcium-dependent cell-cell adhesion molecules, and protocadherins constitute a subfamily of nonclassic cadherins. Protocadherin beta 13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
VE:
1 * 100 µl
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-IFN-gamma Rat Monoclonal Antibody [clone: XMG1.2]
Lieferant:
Sigma-Aldrich
Beschreibung:
(±)-γ-Undecalacton, Sigma-Aldrich®
Artikel-Nr:
(PRSI91-417)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-417
Lokale Artikelnummer::
PRSI91-417
Beschreibung:
Human Fractalkine (CX3CL1) is a member of the CX3C family of chemokines. Human Fractalkine contains both chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid). The mucin-like stalk permits it to bind to the cell surface.
VE:
1 * 50 µG
Lieferant:
MP Biomedicals
Beschreibung:
Lecithin is the major membrane phospholipid in eukaryotic cells. In addition to being the major structural component of cellular membranes, it serves as a reservoir for several lipid messengers. It is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, plateletactivating factor, and arachidonic acid.
Leithin is used for preparation of vesicle, suspensions commonly called liposomes or as monolayers.
A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.
Soluble in fat, paraffin, ether, ethanol, chlorinated hydrocarbons. Dispersible in water.
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-TCR gamma/delta Hamster Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: GL3]
Artikel-Nr:
(PRSI91-060)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-060
Lokale Artikelnummer::
PRSI91-060
Beschreibung:
Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate immune responses. IL-1F10 was expressed in fetal skin, spleen and tonsil, mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. IL-1F10 binds soluble IL-1 receptor type 1 and may be implicated in regulating adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-095)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-095
Lokale Artikelnummer::
PRSI28-095
Beschreibung:
VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.
VE:
1 * 50 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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