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2-Methyl-5-(trifluoromethyl)benzyl+alcohol
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2-Methyl-5-(trifluoromethyl)benzyl+alcohol
Artikel-Nr:
(BOSSBS-13627R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13627R-A555
Lokale Artikelnummer::
BOSSBS-13627R-A555
Beschreibung:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter’s syndrome which is characterized by renal salt-wasting and low blood pressure.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Natriumhydroxid ≥98%, Plätzchen, EMPROVE® ESSENTIAL Ph. Eur., BP, FCC, JP, NF, E524, SAFC®
Artikel-Nr:
(BOSSBS-12125R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12125R-A555
Lokale Artikelnummer::
BOSSBS-12125R-A555
Beschreibung:
The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12125R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12125R-A350
Lokale Artikelnummer::
BOSSBS-12125R-A350
Beschreibung:
The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13298R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13298R-A647
Lokale Artikelnummer::
BOSSBS-13298R-A647
Beschreibung:
CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12125R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12125R-FITC
Lokale Artikelnummer::
BOSSBS-12125R-FITC
Beschreibung:
The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10307R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10307R-A647
Lokale Artikelnummer::
BOSSBS-10307R-A647
Beschreibung:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10307R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10307R
Lokale Artikelnummer::
BOSSBS-10307R
Beschreibung:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
VE:
1 * 100 µl
Lieferant:
Honeywell Chemicals
Beschreibung:
Natriumhydroxid ≥98%, Plätzchen, Puriss. p.a. ACS, Reag. Ph. Eur. (max. 0,02% K), Fluka™
Lieferant:
Sigma-Aldrich
Beschreibung:
L(-)-Äpfelsäure Mononatriumsalz, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-1889R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1889R
Lokale Artikelnummer::
BOSSBS-1889R
Beschreibung:
SCN1A is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript
VE:
1 * 100 µl
Artikel-Nr:
(SIALB8049-5TAB)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
B8049-5TAB
Lokale Artikelnummer::
SIALB8049-5TAB
Beschreibung:
X-Gluc (5-Brom-4-chlor-3-indolyl-ß-D-glucuronid Cyclohexylammoniumsalz, X-GlcA), Sigma-Aldrich®
VE:
1 * 5 Tablet
Lieferant:
Sigma-Aldrich
Beschreibung:
EDTA Dinatriumsalz Dihydrat, Sigma-Aldrich®
Lieferant:
Merck
Beschreibung:
Natriumhydroxid 25%, EMPROVE® EXPERT für die biopharmazeutische Produktion eisenarm, SAFC®
Lieferant:
Honeywell Chemicals
Beschreibung:
Natriumhydroxid 0.5 M NaOH (0.5N) volumetrische Lösung, Fluka™
Lieferant:
Thermo Scientific
Beschreibung:
EDTA Dinatriumsalz Dihydrat 99+% ACS
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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