Trisodium+naphthalene-1,3,5-trisulphonate
Artikel-Nr:
(BOSSBS-11753R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11753R
Lokale Artikelnummer::
BOSSBS-11753R
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(PROOBP423)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
BP423
Lokale Artikelnummer::
PROOBP423
Beschreibung:
Vitamin K1 (Phytomenadion, Phyllochinon)
VE:
1 * 0,25 mL
Artikel-Nr:
(EHERC16986102)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C16986102
Lokale Artikelnummer::
EHERC16986102
Beschreibung:
Sudan II
VE:
1 * 100 mg
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-(Hydroxymethyl)-2-hydroxynaphthalin
Lieferant:
Biotium
Beschreibung:
In Western blotting, this antibody detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
Artikel-Nr:
(BNUM0342-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0342-50
Lokale Artikelnummer::
BTIUBNUM0342-50
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Artikel-Nr:
(FLUO018322-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018322-5G
Lokale Artikelnummer::
FLUO018322-5G
Beschreibung:
2-Brom-1,3,5-trichlorbenzol
VE:
1 * 5 g
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Lieferant:
Biotium
Beschreibung:
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Artikel-Nr:
(BOSSBS-12948R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12948R
Lokale Artikelnummer::
BOSSBS-12948R
Beschreibung:
CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Tolnaftate
Lieferant:
Thermo Scientific
Beschreibung:
2,4-Bis(chlormethyl)-1,3,5-trimethylbenzol
Artikel-Nr:
(ACRO467901000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
467901000
Lokale Artikelnummer::
ACRO467901000
Beschreibung:
Chemical probes can be used to help establish the
relationship between a molecular target and the broader biological consequences of modulating that target in cells or organisms.
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-9720R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9720R-FITC
Lokale Artikelnummer::
BOSSBS-9720R-FITC
Beschreibung:
C10orf27, also known as spatial, is a 351 amino acid cytoplasmic protein belonging to the spatial family. C10orf27 is suggested to play a role in spermatid differentiation. Existing as two alternatively spliced isoforms, C10orf27 is widely expressed in multiple tissues, including brain, thymus and testis. C10orf27 may be associated with multiple sclerosis (MS) susceptibility and pathogenesis. MS is an inflammatory disease that causes gradual destruction of myelin in the central nervous system. C10orf27 is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13209R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13209R
Lokale Artikelnummer::
BOSSBS-13209R
Beschreibung:
FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13209R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13209R-CY5
Lokale Artikelnummer::
BOSSBS-13209R-CY5
Beschreibung:
FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.
VE:
1 * 100 µl
Preis auf Anfrage
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