4-Chloro-3-fluorobenzoic+acid
Artikel-Nr:
(BOSSBS-0615R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0615R
Lokale Artikelnummer::
BOSSBS-0615R
Beschreibung:
Anti-BIRC5 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15244R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15244R-A555
Lokale Artikelnummer::
BOSSBS-15244R-A555
Beschreibung:
C6orf226.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15480R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15480R-CY5
Lokale Artikelnummer::
BOSSBS-15480R-CY5
Beschreibung:
Hho1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8608R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8608R-A680
Lokale Artikelnummer::
BOSSBS-8608R-A680
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7094R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7094R-A680
Lokale Artikelnummer::
BOSSBS-7094R-A680
Beschreibung:
This gene is specifically expressed in the thymus, and encodes a protein that is localised to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6894R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6894R-A750
Lokale Artikelnummer::
BOSSBS-6894R-A750
Beschreibung:
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11771R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11771R-A680
Lokale Artikelnummer::
BOSSBS-11771R-A680
Beschreibung:
SCA11 is a 1244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8235R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8235R-A750
Lokale Artikelnummer::
BOSSBS-8235R-A750
Beschreibung:
No data available.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15339R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15339R-A555
Lokale Artikelnummer::
BOSSBS-15339R-A555
Beschreibung:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf7 gene product has been provisionally designated C9orf7 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11094R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11094R
Lokale Artikelnummer::
BOSSBS-11094R
Beschreibung:
Anti-NCAM2 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13043R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13043R-A680
Lokale Artikelnummer::
BOSSBS-13043R-A680
Beschreibung:
The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10366R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10366R-A680
Lokale Artikelnummer::
BOSSBS-10366R-A680
Beschreibung:
Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1055R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1055R-A555
Lokale Artikelnummer::
BOSSBS-1055R-A555
Beschreibung:
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9646R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9646R-CY7
Lokale Artikelnummer::
BOSSBS-9646R-CY7
Beschreibung:
C17orf75 is a 396 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9735R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9735R-CY7
Lokale Artikelnummer::
BOSSBS-9735R-CY7
Beschreibung:
The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5’ and 3’ splice sites, thereby releasing introns and free tRNA molecules with 2',3' cyclic phosphates and 5'-OH termini. In addition to its role in pre-tRNA splicing, the heterotetrameric endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA and pre-mRNA splicing events. TSEN2 (tRNA-splicing endonuclease subunit Sen2), also known as tRNA-intron endonuclease Sen2, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex. There are three isoforms of TSEN2 that are produced as a result of alternative splicing events. Isoform 1 seems to carry the active site for 5’-splice site cleavage. Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, which is characterized by progressive microencephaly with epilepsy, extrapyramidal dyskinesia and chorea without spinal cord findings.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6384R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6384R-FITC
Lokale Artikelnummer::
BOSSBS-6384R-FITC
Beschreibung:
C10orf28 is a 792 amino acid protein that exists as three alternatively spliced isoforms. The gene encoding C10orf28 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
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