beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Artikel-Nr:
(BOSSBS-12175R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12175R-A350
Lokale Artikelnummer::
BOSSBS-12175R-A350
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0400R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0400R-FITC
Lokale Artikelnummer::
BOSSBS-0400R-FITC
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1657R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1657R-A680
Lokale Artikelnummer::
BOSSBS-1657R-A680
Beschreibung:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1657R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1657R-CY5.5
Lokale Artikelnummer::
BOSSBS-1657R-CY5.5
Beschreibung:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3062R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3062R
Lokale Artikelnummer::
BOSSBS-3062R
Beschreibung:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP alpha, CEBP delta, and CEBP gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL1 response element in the IL6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
VE:
1 * 100 µl
Artikel-Nr:
(CRM40909)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
CRM40909
Lokale Artikelnummer::
SUPLCRM40909
Beschreibung:
Organic Standard, alpha and beta-Thujone solution, Ampule of 1 ml
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-9446R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9446R-A647
Lokale Artikelnummer::
BOSSBS-9446R-A647
Beschreibung:
AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein. The human AMPKg1 gene encodes a 331 amino acid protein. Human AMPKg2 and AMPKg3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1657R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1657R-A555
Lokale Artikelnummer::
BOSSBS-1657R-A555
Beschreibung:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8541R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8541R-A680
Lokale Artikelnummer::
BOSSBS-8541R-A680
Beschreibung:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognises alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognises also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties. IFN-g is secreted by several types of immune cells, which allow the cytokine to modulate innate immunity, when secreted by NK and NKT cells, and to function in supporting adaptive immunity when secreted by Th1 and CD8+ T cells (CTLs).
Artikel-Nr:
(BOSSBS-11339R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11339R-A750
Lokale Artikelnummer::
BOSSBS-11339R-A750
Beschreibung:
Members of the calsyntenin protein family are localised to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(30638-10MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
30638-10MG
Lokale Artikelnummer::
SUPL30638-10MG
Beschreibung:
Organic Standard, Petunidin 3-O-beta-D-glucoside chloride, ≥95.0% (HPLC)
VE:
1 * 10 mg
Artikel-Nr:
(BOSSBS-5422R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5422R
Lokale Artikelnummer::
BOSSBS-5422R
Beschreibung:
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II.PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen.
VE:
1 * 100 µl
Lieferant:
IMMUNOLOGIC
Beschreibung:
Anti-lambda detects surface immunoglobulin on normal and neoplastic B-cells. Its staining is seen in B-cell follicles of human lymphoid tissue. When dealing with B-cell neoplasms, the determination of light chain ratios remains helpful. Most B-cell lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda positive cells. If only a single light chain type is detected, a lymphoproliferative disorder is very likely.<sup>1-3</sup>
Artikel-Nr:
(APOSBICY1017-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BICY1017-5G
Lokale Artikelnummer::
APOSBICY1017-5G
Beschreibung:
Heptakis(6-deoxy-6-chloro)-beta-cyclodexrin
VE:
1 * 5 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Soluble carboxymethyl-beta-cyclodextrin polymer
Preis auf Anfrage
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