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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Artikel-Nr:
(BOSSBS-0174R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0174R-CY5.5
Lokale Artikelnummer::
BOSSBS-0174R-CY5.5
Beschreibung:
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1407R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1407R-FITC
Lokale Artikelnummer::
BOSSBS-1407R-FITC
Beschreibung:
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2600R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2600R-FITC
Lokale Artikelnummer::
BOSSBS-2600R-FITC
Beschreibung:
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5791R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5791R-A350
Lokale Artikelnummer::
BOSSBS-5791R-A350
Beschreibung:
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11260R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11260R-CY3
Lokale Artikelnummer::
BOSSBS-11260R-CY3
Beschreibung:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11260R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11260R-A750
Lokale Artikelnummer::
BOSSBS-11260R-A750
Beschreibung:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11260R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11260R-A680
Lokale Artikelnummer::
BOSSBS-11260R-A680
Beschreibung:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI3239)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3239
Lokale Artikelnummer::
PRSI3239
Beschreibung:
TRIM5 gamma Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. While a function has not yet been assigned to TRIM5gamma, it is known that expression of TRIM5 alpha variants from humans, rhesus monkeys, and African green monkeys enable resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. Furthermore, the TRIM5 delta isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-9317R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9317R-A488
Lokale Artikelnummer::
BOSSBS-9317R-A488
Beschreibung:
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9318R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9318R-A750
Lokale Artikelnummer::
BOSSBS-9318R-A750
Beschreibung:
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9317R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9317R-A647
Lokale Artikelnummer::
BOSSBS-9317R-A647
Beschreibung:
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9318R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9318R-A350
Lokale Artikelnummer::
BOSSBS-9318R-A350
Beschreibung:
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5457R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5457R-CY5
Lokale Artikelnummer::
BOSSBS-5457R-CY5
Beschreibung:
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2600R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2600R-A647
Lokale Artikelnummer::
BOSSBS-2600R-A647
Beschreibung:
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8542R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8542R-CY7
Lokale Artikelnummer::
BOSSBS-8542R-CY7
Beschreibung:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5791R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5791R-FITC
Lokale Artikelnummer::
BOSSBS-5791R-FITC
Beschreibung:
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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