beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Artikel-Nr:
(BOSSBS-11181R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11181R-A350
Lokale Artikelnummer::
BOSSBS-11181R-A350
Beschreibung:
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Oct 2009].
VE:
1 * 100 µl
Artikel-Nr:
(PRSI26-612)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-612
Lokale Artikelnummer::
PRSI26-612
Beschreibung:
4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
VE:
1 * 50 µG
Lieferant:
HICHROM GAS CHROMATOGRAPHY
Beschreibung:
Nützlich für die Analyse chiraler Verbindungen in Duftstoffen, Pestiziden und Pharmazeutika, bei denen die Bestimmung des Enantiomerenverhältnisses in einer Probe erforderlich ist.
Artikel-Nr:
(BOSSBS-9357R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9357R-CY7
Lokale Artikelnummer::
BOSSBS-9357R-CY7
Beschreibung:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9357R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9357R-A647
Lokale Artikelnummer::
BOSSBS-9357R-A647
Beschreibung:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI29-771)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-771
Lokale Artikelnummer::
PRSI29-771
Beschreibung:
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3724R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3724R-A680
Lokale Artikelnummer::
BOSSBS-3724R-A680
Beschreibung:
This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9357R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9357R-A555
Lokale Artikelnummer::
BOSSBS-9357R-A555
Beschreibung:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4687R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4687R-HRP
Lokale Artikelnummer::
BOSSBS-4687R-HRP
Beschreibung:
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5015R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5015R-A488
Lokale Artikelnummer::
BOSSBS-5015R-A488
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10150R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10150R-HRP
Lokale Artikelnummer::
BOSSBS-10150R-HRP
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2454R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2454R-A350
Lokale Artikelnummer::
BOSSBS-2454R-A350
Beschreibung:
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2454R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2454R-HRP
Lokale Artikelnummer::
BOSSBS-2454R-HRP
Beschreibung:
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10421R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10421R-A680
Lokale Artikelnummer::
BOSSBS-10421R-A680
Beschreibung:
Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin Signalling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (referenced from swissprot).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3299R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3299R-A680
Lokale Artikelnummer::
BOSSBS-3299R-A680
Beschreibung:
E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1578R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1578R
Lokale Artikelnummer::
BOSSBS-1578R
Beschreibung:
The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response; it modulates adaptive immunity.
VE:
1 * 100 µl
Preis auf Anfrage
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