cis-6-Amino-cyclohex-3-enecarboxylic+acid
Artikel-Nr:
(BOSSBS-13153R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13153R-A647
Lokale Artikelnummer::
BOSSBS-13153R-A647
Beschreibung:
FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13153R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13153R-FITC
Lokale Artikelnummer::
BOSSBS-13153R-FITC
Beschreibung:
FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.
VE:
1 * 100 µl
Artikel-Nr:
(ABCRAB136367.0500)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB136367.0500
Lokale Artikelnummer::
ABCRAB136367.0500
Beschreibung:
6-Amino-1-naphthalinsulfonsäure ≥97,0% (durch HPLC, titrimetrische Analyse)
VE:
1 * 500 g
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Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Amino-5-thiazolcarbonsäure
Artikel-Nr:
(BOSSBS-12096R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12096R-CY7
Lokale Artikelnummer::
BOSSBS-12096R-CY7
Beschreibung:
Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Amino-4-thiazolcarbonsäure
Artikel-Nr:
(BOSSBS-10348R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10348R-A750
Lokale Artikelnummer::
BOSSBS-10348R-A750
Beschreibung:
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R-A680
Lokale Artikelnummer::
BOSSBS-12343R-A680
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinases, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12947R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12947R-A647
Lokale Artikelnummer::
BOSSBS-12947R-A647
Beschreibung:
CRP2BP is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously expressed nuclear protein, with highest expression in skeletal muscle and heart.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12947R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12947R-A488
Lokale Artikelnummer::
BOSSBS-12947R-A488
Beschreibung:
CRP2BP is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously expressed nuclear protein, with highest expression in skeletal muscle and heart.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12096R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12096R-FITC
Lokale Artikelnummer::
BOSSBS-12096R-FITC
Beschreibung:
Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12096R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12096R-A488
Lokale Artikelnummer::
BOSSBS-12096R-A488
Beschreibung:
Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8112R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8112R-CY3
Lokale Artikelnummer::
BOSSBS-8112R-CY3
Beschreibung:
CCDC117 is a 279 amino acid protein that is expressed as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 22. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8017R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8017R-A488
Lokale Artikelnummer::
BOSSBS-8017R-A488
Beschreibung:
CLN6, a 311 amino acid protein, has seven predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12906R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12906R-HRP
Lokale Artikelnummer::
BOSSBS-12906R-HRP
Beschreibung:
KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12353R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12353R-A750
Lokale Artikelnummer::
BOSSBS-12353R-A750
Beschreibung:
HES7 is a 225 amino acid transcriptional repressor protein. localised to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterised by deformities of the chest and spine.
VE:
1 * 100 µl
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