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(\\u00B1)11(12)-EET+methyl+ester
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(\\u00B1)11(12)-EET+methyl+ester
Artikel-Nr:
(BOSSBS-0268R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0268R-HRP
Lokale Artikelnummer::
BOSSBS-0268R-HRP
Beschreibung:
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(APOSIN1204-50G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
IN1204-50G
Lokale Artikelnummer::
APOSIN1204-50G
Beschreibung:
Bariumnitrat 99,9%
VE:
1 * 50 g
Artikel-Nr:
(BOSSBS-11702R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R
Lokale Artikelnummer::
BOSSBS-11702R
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R
Lokale Artikelnummer::
BOSSBS-12919R
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11702R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R-CY7
Lokale Artikelnummer::
BOSSBS-11702R-CY7
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0439R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0439R-CY5.5
Lokale Artikelnummer::
BOSSBS-0439R-CY5.5
Beschreibung:
Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0644R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R-A680
Lokale Artikelnummer::
BOSSBS-0644R-A680
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-5968R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5968R-A750
Lokale Artikelnummer::
BOSSBS-5968R-A750
Beschreibung:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5968R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5968R-A488
Lokale Artikelnummer::
BOSSBS-5968R-A488
Beschreibung:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
VE:
1 * 100 µl
Lieferant:
Biowest
Beschreibung:
Gentamycin sulphate acts against Gram-negative, Gram-positive bacteria and mycoplasma.
Artikel-Nr:
(BOSSBS-8241R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8241R-A555
Lokale Artikelnummer::
BOSSBS-8241R-A555
Beschreibung:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2924R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2924R-A350
Lokale Artikelnummer::
BOSSBS-2924R-A350
Beschreibung:
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11693R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11693R-A555
Lokale Artikelnummer::
BOSSBS-11693R-A555
Beschreibung:
Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription (PubMed:19515850, PubMed:21700224). Contributes to the mRNA splicing efficiency and splice site selection (PubMed:19515850). Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (PubMed:19515850, PubMed:21700224). Required for the 3' transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation (By similarity). Involved in DNA double-strand breaks damage response generated by oxidative stress (PubMed:17562789). In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage (PubMed:24105744). Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI) (By similarity). May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription (PubMed:21112256). Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated signaling pathways. Inhibits retinoic acid-induced apoptosis (PubMed:21576111).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0644R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R
Lokale Artikelnummer::
BOSSBS-0644R
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12900R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12900R-CY5
Lokale Artikelnummer::
BOSSBS-12900R-CY5
Beschreibung:
General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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