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trans-1,4-Cyclohexanedimethanol
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trans-1,4-Cyclohexanedimethanol
Artikel-Nr:
(BOSSBS-11884R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11884R
Lokale Artikelnummer::
BOSSBS-11884R
Beschreibung:
The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Methoxy-2,4-dihydro-1,4-benzoxazin-3-one 98%
Artikel-Nr:
(APOSOR32323-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR32323-1G
Lokale Artikelnummer::
APOSOR32323-1G
Beschreibung:
5,6-Dibromocyclohex-2-ene-1,4-dione, tech
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-[2-Nitro-4-(trifluoromethyl)phenyl-[1,4]diazepane hydrochloride
Artikel-Nr:
(BLDPBD01265490-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01265490-1G
Lokale Artikelnummer::
BLDPBD01265490-1G
Beschreibung:
Dibenzo[b,e][1,4]dioxine-2,3,7,8-tetraamine tetrahydrochloride 97%
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD753067-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD753067-1G
Lokale Artikelnummer::
BLDPBD753067-1G
Beschreibung:
7-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-3541R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3541R-A647
Lokale Artikelnummer::
BOSSBS-3541R-A647
Beschreibung:
Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD00784450-100)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00784450-100
Lokale Artikelnummer::
BLDPBD00784450-100
Beschreibung:
2-Methyl-2,3-dihydrophthalazine-1,4-dione 98%
VE:
1 * 100 mg
Artikel-Nr:
(BLDPBD593635-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD593635-100MG
Lokale Artikelnummer::
BLDPBD593635-100MG
Beschreibung:
1,4-Di(pyridin-4-yl)butane 97%
VE:
1 * 100 mg
Artikel-Nr:
(APOSPC7866-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC7866-5G
Lokale Artikelnummer::
APOSPC7866-5G
Beschreibung:
1,4-Difluoro-2,3-dimethylbenzene 96%
VE:
1 * 5 g
Lieferant:
Merck
Beschreibung:
Tetrachlor-p-benzochinon zur Synthese, Sigma-Aldrich®
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Methyl-1,4-phenylene bis{4-[3-(acryloyloxy)propoxy]benzoate}
Artikel-Nr:
(APOSOR52308-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR52308-1G
Lokale Artikelnummer::
APOSOR52308-1G
Beschreibung:
tert-Butyl 4-hydroxy-1,4'-bipiperidine-1'-carboxylate 98%
VE:
1 * 1 g
Lieferant:
Biotium
Beschreibung:
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
Lieferant:
Biotium
Beschreibung:
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
Artikel-Nr:
(BOSSBS-8333R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-CY5
Lokale Artikelnummer::
BOSSBS-8333R-CY5
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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