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4\'-Bromo-3\'-iodoacetophenone
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4\'-Bromo-3\'-iodoacetophenone
Artikel-Nr:
(BOSSBS-1317R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1317R-CY5.5
Lokale Artikelnummer::
BOSSBS-1317R-CY5.5
Beschreibung:
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11180R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11180R-A680
Lokale Artikelnummer::
BOSSBS-11180R-A680
Beschreibung:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyse the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localisation, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(ABNOKA6734.1KIT)
Lieferant:
Abnova
Hersteller-Artikelnummer::
KA6734.1KIT
Lokale Artikelnummer::
ABNOKA6734.1KIT
Beschreibung:
Herpes Simplex Virus I+II IgG ELISA Kit is a qualitative determination of IgG class antibodies against Herpes Simplex Virus 1+2 (HSV) in human serum or plasma.
VE:
1 * 1 KIT
Lieferant:
Thermo Scientific
Beschreibung:
Calciumsulfat, Drierite™ 10-20 mesh, mit Indikator (Kobalt (II) Chlorid)
Artikel-Nr:
(SIAL254231-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
254231-25G
Lokale Artikelnummer::
SIAL254231-25G
Beschreibung:
Bleiselenid, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(SIALZ1001-500G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
Z1001-500G
Lokale Artikelnummer::
SIALZ1001-500G
Beschreibung:
Zinksulfat Heptahydrat, Sigma-Aldrich®
VE:
1 * 500 g
Artikel-Nr:
(USBI036361)
Lieferant:
US Biological
Hersteller-Artikelnummer::
036361
Lokale Artikelnummer::
USBI036361
Beschreibung:
Anti-GTF2I Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Lieferant:
Stemcell Technologies
Beschreibung:
Rat monoclonal IgG2b, antibody against mouse MHC Class II (I-A/I-E), FITC-conjugated.
Lieferant:
Thermo Orion
Beschreibung:
Orion™ AQUAfast tablet reagents perform colorimetric measurements of common water parameters with convenient, rapidly dissolving tablets.
Artikel-Nr:
(PRSI90-360)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-360
Lokale Artikelnummer::
PRSI90-360
Beschreibung:
Kynurenine aminotransferases (KATs) are pyridoxal-5’-phosphate-dependent enzymes that catalyse the conversion of L-kynurenine into kynurenic acid, a neuroactive metabolite whose unbalancing is associated with a number of brain disorders. Biochemical and structural investigations revealed that L-kynurenine (L-KYN) recognition by hKAT II is achieved by exploiting structural features that are peculiar of this isoform, thus offering the possibility to select/design inhibitor molecules specifically targeting hKAT II to be used as modulators of kynurenic acid synthesis in the CNS. hKAT II is one of the aminotransferases involved in the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of L-kynurenine (L-KYN) to kynurenic acid (KYNA) in the central nervous system. When assayed in vitro the protein also displays beta-elimination activity.
VE:
1 * 50 µG
Lieferant:
Sartorius
Beschreibung:
The arium® comfort II system supplies ASTM Type I and Type II ultrapure water and is used for both critical applications and routine analyses. Streamlined to incorporate only the most important functions for the production of high quality ultrapure water, the arium® comfort II is a cost effective alternative for the discerning user that is also very easy to use.
Lieferant:
EDWARDS HIGH VACUUM METTLER
Beschreibung:
ATEX RV pumps have an external ATEX classification of Ex II 2G IIC T4 or Ex II 2G IIB T4 and internal ATEX classification Ex II 3G c IIB T4. They are suitable for use in potentially explosive atmospheres such as hazardous area pumping. They are supplied with the gas ballast port which must be fitted with an inert gas purge while pumping flammable gasses or vapours to dilute such gases or vapours below the lower explosive limit.
Lieferant:
Honeywell Chemicals
Beschreibung:
Zinkacetat Dihydrat 99-102%, Puriss., erfüllt analytische Spezifikationen von DAB, E650, Fluka™
Lieferant:
Bernd Kraft
Beschreibung:
Cadmiumacetat Dihydrat, reinst
Artikel-Nr:
(BOSSBS-8444R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-HRP
Lokale Artikelnummer::
BOSSBS-8444R-HRP
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3427R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3427R-A555
Lokale Artikelnummer::
BOSSBS-3427R-A555
Beschreibung:
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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