2\'-Chlor-5\'-methylbiphenyl-3-carbonsäure
Artikel-Nr:
(USBIM3886-08E)
Lieferant:
US Biological
Hersteller-Artikelnummer::
M3886-08E
Lokale Artikelnummer::
USBIM3886-08E
Beschreibung:
Anti-MHC Class 2, I-Ab Mouse Monoclonal Antibody
VE:
1 * 500 µG
Artikel-Nr:
(BOSSBS-8671R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8671R-A555
Lokale Artikelnummer::
BOSSBS-8671R-A555
Beschreibung:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5164R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5164R-A488
Lokale Artikelnummer::
BOSSBS-5164R-A488
Beschreibung:
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5164R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5164R-A350
Lokale Artikelnummer::
BOSSBS-5164R-A350
Beschreibung:
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI36-110)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-110
Lokale Artikelnummer::
PRSI36-110
Beschreibung:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3697R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3697R-A750
Lokale Artikelnummer::
BOSSBS-3697R-A750
Beschreibung:
CTR9 is a component of the PAF (polymerase-associated factor) complex which interacts with histone-modifying enzymes and RNA polymerase II and plays a role in a number of transcription-related processes. Recent studies show that CTR9 can regulate IL-6-responsive gene transcription by influencing histone methylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5036R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5036R-A750
Lokale Artikelnummer::
BOSSBS-5036R-A750
Beschreibung:
Apolipoprotein C-II (apoCII) is in found in chylomicrons (large lipoprotein particles absorbed from the gastrointestinal tract) and VLDL (large lipoproteins that are broken down to eventually form LDL). ApoCII activates the enzyme lipoprotein lipase, which hydrolyses triglycerides and thus provides free fatty acids for cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6851R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6851R-A555
Lokale Artikelnummer::
BOSSBS-6851R-A555
Beschreibung:
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4260R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4260R-A488
Lokale Artikelnummer::
BOSSBS-4260R-A488
Beschreibung:
ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7728R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7728R-A647
Lokale Artikelnummer::
BOSSBS-7728R-A647
Beschreibung:
SMC4 is a central component of the condensin complex, which is required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-A750
Lokale Artikelnummer::
BOSSBS-6076R-A750
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6076R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6076R-CY7
Lokale Artikelnummer::
BOSSBS-6076R-CY7
Beschreibung:
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7070R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7070R-A750
Lokale Artikelnummer::
BOSSBS-7070R-A750
Beschreibung:
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6295R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6295R-A555
Lokale Artikelnummer::
BOSSBS-6295R-A555
Beschreibung:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6295R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6295R-A488
Lokale Artikelnummer::
BOSSBS-6295R-A488
Beschreibung:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6295R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6295R-CY7
Lokale Artikelnummer::
BOSSBS-6295R-CY7
Beschreibung:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
VE:
1 * 100 µl
Preis auf Anfrage
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