Drucken

Anti-SLITRK4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
Ratings: (keine Bewertung)

Gesamtbewertung: 0
Bewertung: von 5

BS-11957R-A680
BOSSBS-11957R-A680EA 890 EUR
BOSSBS-11957R-A680
Anti-SLITRK4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, specifically in the thalamus, hypothalamus, subventricular zone, CA3 region of the hippocampus and cortical plate. SLITRK4 may be upregulated in some astrocytic brain tumours such as glioblastomas, astrocytomas and primitive neuroectodermal tumours. As compared with its family member SLITRK2, SLITRK4 only weakly suppresses neurite outgrowth. A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, as well as the ARL5B and PLA2G7 genes, may be involved in the pathogenesis of preeclampsia.

Type: Primary
Antigen: SLITRK4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 251-350/837
Host: Rabbit
Isotype: IgG
Reactivity:
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR