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Anti-PXR Rabbit Polyclonal Antibody (Alexa Fluor® 680)

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BS-2334R-A680
BOSSBS-2334R-A680EA 899 EUR
BOSSBS-2334R-A680
Anti-PXR Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.

Type: Primary
Antigen: PXR
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-150/434
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Pig
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