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Anti-BARD1 Rabbit Polyclonal Antibody (Cy5®)

Lieferant: Bioss
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BS-4291R-CY5
BOSSBS-4291R-CY5EA 909 EUR
BOSSBS-4291R-CY5
Anti-BARD1 Rabbit Polyclonal Antibody (Cy5®)
Antikörper
Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: BARD1
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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