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Antikörper
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
Artikel-Nr:
(AVIVARP61099_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP61099_P050
Lokale Artikelnummer::
AVIVARP61099_P050
Beschreibung:
Anti-VCL Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(ABGEAP14557A)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP14557A
Lokale Artikelnummer::
ABGEAP14557A
Beschreibung:
Anti-KLK10 Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(USBIP9007-33F)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9007-33F
Lokale Artikelnummer::
USBIP9007-33F
Beschreibung:
Anti-PGRMC2 Mouse Monoclonal Antibody [clone: 3C11]
VE:
1 * 50 µG
Artikel-Nr:
(USBIA2291)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A2291
Lokale Artikelnummer::
USBIA2291
Beschreibung:
Anti-Apramycin Sheep Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1460R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1460R-CY3
Lokale Artikelnummer::
BOSSBS-1460R-CY3
Beschreibung:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(USBI134444)
Lieferant:
US Biological
Hersteller-Artikelnummer::
134444
Lokale Artikelnummer::
USBI134444
Beschreibung:
Anti-HAVCR1 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
Artikel-Nr:
(BOSSBS-6308R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6308R-A680
Lokale Artikelnummer::
BOSSBS-6308R-A680
Beschreibung:
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(AVIVARP51761_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP51761_P050
Lokale Artikelnummer::
AVIVARP51761_P050
Beschreibung:
Anti-CYP1B1 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBI039192-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
039192-AP
Lokale Artikelnummer::
USBI039192-AP
Beschreibung:
Anti-NUBP1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBI040808-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040808-AP
Lokale Artikelnummer::
USBI040808-AP
Beschreibung:
Anti-RAF1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-6000R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6000R-A488
Lokale Artikelnummer::
BOSSBS-6000R-A488
Beschreibung:
DACH1 is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a member of the Ski gene family and is thought to be involved in eye development. Four alternatively spliced transcripts encoding different isoforms have been described for this gene. (from Entrez gene). DACH1 has also been found to inhibit oncogene-mediated breast tumor growth via downregulation of cyclin D1. Expression of DACH1 has been found to inversely correlate with metastasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2222R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2222R
Lokale Artikelnummer::
BOSSBS-2222R
Beschreibung:
Anti-cellulase Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
PAb122 binds to the C-terminus (aa370-378) of both wild type and mutated p53. When microinjected into nuclei, PAb122 blocked re-entry into the S-phase of the cell cycle. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 Binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. p53 Is the most commonly mutated gene in spontaneously occurring human cancers. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation.
Artikel-Nr:
(USBI034699-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
034699-HRP
Lokale Artikelnummer::
USBI034699-HRP
Beschreibung:
Anti-DNAJB12 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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