Antikörper
Artikel-Nr:
(BOSSBS-11243R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11243R-A488
Lokale Artikelnummer::
BOSSBS-11243R-A488
Beschreibung:
Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.
VE:
1 * 100 µl
Artikel-Nr:
(USBI032051)
Lieferant:
US Biological
Hersteller-Artikelnummer::
032051
Lokale Artikelnummer::
USBI032051
Beschreibung:
Anti-ARHGEF33 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(ABGEAP2739A)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP2739A
Lokale Artikelnummer::
ABGEAP2739A
Beschreibung:
Anti-VIM Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(USBI029447)
Lieferant:
US Biological
Hersteller-Artikelnummer::
029447
Lokale Artikelnummer::
USBI029447
Beschreibung:
Anti-CNPase Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 13A169]
VE:
1 * 100 Tests
Artikel-Nr:
(USBIM2363-01-100)
Lieferant:
US Biological
Hersteller-Artikelnummer::
M2363-01-100
Lokale Artikelnummer::
USBIM2363-01-100
Beschreibung:
Anti-MAP Kinase p44, p42, Mouse Monoclonal Antibody [clone: 6D69]
VE:
1 * 100 µG
Artikel-Nr:
(ABGEAP18177B)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP18177B
Lokale Artikelnummer::
ABGEAP18177B
Beschreibung:
Anti-MS4A14 Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(BOSSBS-7874R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7874R
Lokale Artikelnummer::
BOSSBS-7874R
Beschreibung:
SART1 encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri snRNP to the pre spliceosome in the spliceosome assembly pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5945R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5945R-CY5
Lokale Artikelnummer::
BOSSBS-5945R-CY5
Beschreibung:
May have regulatory role in cell division or differentiation in response to extracellular signals.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Artikel-Nr:
(BOSSBS-9636R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9636R-CY7
Lokale Artikelnummer::
BOSSBS-9636R-CY7
Beschreibung:
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(AVIVARP61709_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP61709_P050
Lokale Artikelnummer::
AVIVARP61709_P050
Beschreibung:
Anti-LIPH Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBI041652-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041652-AP
Lokale Artikelnummer::
USBI041652-AP
Beschreibung:
Anti-SGIP1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIZ0510-12B)
Lieferant:
US Biological
Hersteller-Artikelnummer::
Z0510-12B
Lokale Artikelnummer::
USBIZ0510-12B
Beschreibung:
Anti-SLC39A10 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-15174R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15174R-HRP
Lokale Artikelnummer::
BOSSBS-15174R-HRP
Beschreibung:
C3orf32 (chromosome 3 open reading frame 32), also known as fls485, is a 353 amino acid protein encoded by a gene that maps to human chromosome 3p26.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3524R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3524R-HRP
Lokale Artikelnummer::
BOSSBS-3524R-HRP
Beschreibung:
PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
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