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Anti-NELF Rabbit Polyclonal Antibody (Alexa Fluor® 488)

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BOSSBS-11893R-A488EA 437 EUR
BOSSBS-11893R-A488
Anti-NELF Rabbit Polyclonal Antibody (Alexa Fluor® 488)
NELF-A (negative elongation factor A), NELF-B, NELF-C, NELF-D and NELF-E are components of the NELF complex, which is a a structure that negatively regulates Pol II-dependent transcription elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b (P-TEFb) and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. DSIF/NELF inhibition of transcription is prevented by P-TEFb in cooperation with FACT.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: NELF
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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