Hydroxy-2-naphthalenylmethylphosphonic acid ≥95%, kristalliner Feststoff
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HNMPA is a cell impermeable tyrosine kinase inhibitor that blocks receptor serine and tyrosine phosphorylation, including insulin receptor tyrosine kinase activity.
It does not affect protein kinase C or cyclic AMP-dependent protein kinase activities. HNMPA inhibits the insulin-stimulated autophosphorylation of the 95 kDa β-subunit of the insulin receptor with an IC50 value of 200 µM in-vitro.
Formel:
C₁₁H₁₁O₄P MW: 238.2 g/mol Storage Temperature: Gefrierschrank |
CAS-Nummer:
132541-52-7 |
Spezifikation Testergebnisse
Purity | ≥95% |
λmax | 228 nm |
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