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Butyrolactone I ≥99% (durch TLC)

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ENZOBMLCC2101000EA 588.5 EUR
ENZOBMLCC2101000 ENZOBMLCC2100200
Butyrolactone I ≥99% (durch TLC)
Butyrolactone I

CDK inhibitor


Cell permeable and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. G1/S and G2/M transitions, in W138 cells, were inhibited, concurrent with inhibition of the phosphorylations of, respectively, retinoblastoma protein and histone H1. It is an important tool for probing the cellular roles of CDKs. Blocks Fas-induced apoptosis. Displays antitumor activity.

Formel: C₂₄H₂₄O₇
MW: 424,5 g/mol
MDL Number: MFCD03453074
CAS-Nummer: 87414-49-1
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