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Artikel-Nr:
(BOSSBS-9175R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9175R-A488
Lokale Artikelnummer::
BOSSBS-9175R-A488
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF10 (ring finger protein 10), also known as RIE2, is an 811 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Existing as multiple alternatively spliced isoforms, RNF10 interacts with MOX-2 and is thought to regulate its transcription in schwann cells, possibly playing a role in myelin formation. The gene encoding RNF10 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9946R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9946R-A680
Lokale Artikelnummer::
BOSSBS-9946R-A680
Beschreibung:
Encoding over 1100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf29 gene product has been provisionally designated C12orf29 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-CY3
Lokale Artikelnummer::
BOSSBS-11427R-CY3
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(USBI131314)
Lieferant:
US Biological
Hersteller-Artikelnummer::
131314
Lokale Artikelnummer::
USBI131314
Beschreibung:
Anti-INPP5J Mouse Monoclonal Antibody [clone: 2D4]
VE:
1 * 100 µG
Artikel-Nr:
(SCOT299112808)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
299112808
Lokale Artikelnummer::
SCOT299112808
Beschreibung:
Schraubverschluss, DG, Edelstahl (316L) mit Dichtscheibe aus PTFE, Gewinde: GL 45
VE:
1 * 1 ST
Artikel-Nr:
(HECH42992045)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
42992045
Lokale Artikelnummer::
HECH42992045
Beschreibung:
Stopper, DURAN®, hollow, 45/40, Klarglas
VE:
1 * 1 ST
Lieferant:
BELLCO GLASS
Beschreibung:
Zellkultur-Roller, Modular with all-position drive, Sci/ERA™, 45 bottles (8 decks)
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Septen, Silikon weiß/PTFE rot, Härte: 45° shore A, Stärke: 1,3 mm, Ø: 8 mm
Artikel-Nr:
(BOSSBS-12883R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-A555
Lokale Artikelnummer::
BOSSBS-12883R-A555
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Lieferant:
HIRSCHMANN
Beschreibung:
Adapter, A 32 auf A 45, PTFE, Für: ceramus®/solarus® bottle top dispensers
Artikel-Nr:
(BOSSBS-11427R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-A350
Lokale Artikelnummer::
BOSSBS-11427R-A350
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11698R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11698R-CY7
Lokale Artikelnummer::
BOSSBS-11698R-CY7
Beschreibung:
Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein. HYPE is thought to interact with Huntingtin, a protein which induces neurodegeneration when mutated. HYPE also contains two tetratricopeptide repeats (TPR), which may be involved in protein-protein interaction. The gene that encodes HYPE is located on chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-HRP
Lokale Artikelnummer::
BOSSBS-11427R-HRP
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11698R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11698R
Lokale Artikelnummer::
BOSSBS-11698R
Beschreibung:
Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein. HYPE is thought to interact with Huntingtin, a protein which induces neurodegeneration when mutated. HYPE also contains two tetratricopeptide repeats (TPR), which may be involved in protein-protein interaction. The gene that encodes HYPE is located on chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
VE:
1 * 100 µl
Artikel-Nr:
(USBI131437)
Lieferant:
US Biological
Hersteller-Artikelnummer::
131437
Lokale Artikelnummer::
USBI131437
Beschreibung:
Anti-PLCG2 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(VARI12219001)
Lieferant:
VARIAN
Hersteller-Artikelnummer::
12219001
Lokale Artikelnummer::
VARI12219001
Beschreibung:
Bondesil™ Plexa (polymeric) bulk sorbent, 45 µm
VE:
1 * 1 ST
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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